Signal Transduction Antibodies 1

Anti-SLC30A6 Antibody (CAB11644)

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SKU:
CAB11644
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC30A6 Antibody
Antibody SKU:CAB11644
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 252-461 of human SLC30A6 (NP_060434.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 252-461 of human SLC30A6 (NP_060434.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KVLL QTTP PHVI GQLD KLIR EVST LDGV LEVR NEHF WTLG FGSL AGSV HVRI RRDA NEQM VLAH VTNR LYTL VSTL TVQI FKDD WIRP ALLS GPVA ANVL NFSD HHVI PMPL LKGT DDLN PVTS TPAK PSSP PPEF SFNT PGKN VNPV ILLN TQTR PYGF GLNH GHTP YSSM LNQG LGVP GIGA TQGL RTGF TNIP SRYG TNNR IGQP RP
Gene ID:55676
Uniprot:Q6NXT4
Cellular Location:Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane
Calculated MW:47kDa/48kDa/51kDa/55kDa
Observed MW:51kDa
Synonyms:SLC30A6, MST103, MSTP103, ZNT6
Background:
UniProt Protein Function:SLC30A6: Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 2p22.3

Cellular Component: Golgi apparatus; Golgi membrane; membrane

Molecular Function:zinc ion transmembrane transporter activity

Biological Process: response to zinc ion

NCBI Summary:This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques. [provided by RefSeq, Aug 2016]
UniProt Code:Q6NXT4
NCBI GenInfo Identifier:162416263
NCBI Gene ID:55676
NCBI Accession:Q6NXT4.2
UniProt Secondary Accession:Q6NXT4,Q8N5C9, Q96NC3, A5YM45, B7Z901,
UniProt Related Accession:Q6NXT4
Molecular Weight:51kDa
NCBI Full Name:Zinc transporter 6
NCBI Synonym Full Names:solute carrier family 30 member 6
NCBI Official Symbol:SLC30A6  
NCBI Official Synonym Symbols:ZNT6; MST103; MSTP103  
NCBI Protein Information:zinc transporter 6
UniProt Protein Name:Zinc transporter 6
UniProt Synonym Protein Names:Solute carrier family 30 member 6
Protein Family:Zinc transporter
UniProt Gene Name:SLC30A6  
Anti-SLC30A6 Antibody (CAB11644)Western blot analysis of extracts of various cell lines, using SLC30A6 Antibody (CAB11644) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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