Signal Transduction Antibodies 1

Anti-SLC30A1 Antibody (CAB12532)

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SKU:
CAB12532
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC30A1 Antibody
Antibody SKU:CAB12532
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC30A1 (NP_067017.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:THP-1, Rat kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC30A1 (NP_067017.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LHVL GDAL GSVI VVVN ALVF YFSW KGCS EGDF CVNP CFPD PCKA FVEI INST HASV YEAG PCWV LYLD PTLC VVMV CILL YTTY PLLK ESAL ILLQ TVPK Q
Gene ID:7779
Uniprot:Q9Y6M5
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:55kDa
Observed MW:68kDa/70kDa
Synonyms:SLC30A1, ZNT1, ZRC1
Background:
UniProt Protein Function:SLC30A1: May be involved in zinc transport out of the cell. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
UniProt Protein Details:

Protein type:Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: cytoplasm; endoplasmic reticulum; Golgi apparatus; integral to membrane; nuclear membrane; plasma membrane; T-tubule

Molecular Function:calcium channel inhibitor activity; protein binding; zinc ion transmembrane transporter activity

Biological Process: cellular calcium ion homeostasis; cellular zinc ion homeostasis; in utero embryonic development; negative regulation of neurotransmitter secretion; response to zinc ion; transmembrane transport; zinc ion transport

UniProt Code:Q9Y6M5
NCBI GenInfo Identifier:251757423
NCBI Gene ID:7779
NCBI Accession:Q9Y6M5.3
UniProt Secondary Accession:Q9Y6M5,Q0VAK9, Q9BZF6,
UniProt Related Accession:Q9Y6M5
Molecular Weight:
NCBI Full Name:Zinc transporter 1
NCBI Synonym Full Names:solute carrier family 30 member 1
NCBI Official Symbol:SLC30A1  
NCBI Official Synonym Symbols:ZNT1; ZRC1  
NCBI Protein Information:zinc transporter 1
UniProt Protein Name:Zinc transporter 1
UniProt Synonym Protein Names:Solute carrier family 30 member 1
Protein Family:Zinc transporter
UniProt Gene Name:SLC30A1  
UniProt Entry Name:ZNT1_HUMAN
Anti-SLC30A1 Antibody (CAB12532)Western blot analysis of extracts of various cell lines, using SLC30A1 antibody (CAB12532) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-SLC30A1 Antibody (CAB12532)Immunohistochemistry of paraffin-embedded human mammary cancer using SLC30A1 antibody (CAB12532) at dilution of 1:100 (40x lens).
Anti-SLC30A1 Antibody (CAB12532)Immunohistochemistry of paraffin-embedded human stomach using SLC30A1 antibody (CAB12532) at dilution of 1:100 (40x lens).
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