Signal Transduction Antibodies 1

Anti-SLC2A5 Antibody (CAB13650)

(No reviews yet) Write a Review
SKU:
CAB13650
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SLC2A5 Antibody
Antibody SKU:CAB13650
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC2A5 (NP_003030.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Mouse testis, Mouse kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC2A5 (NP_003030.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEQQ DQSM KEGR LTLV LALA TLIA AFGS SFQY GYNV AAVN SPAL LMQQ FYNE TYYG RTGE FMED FPLT LLWS VTVS MFPF GGFI GSLL VGPL VNKF GRKG
Gene ID:6518
Uniprot:P22732
Cellular Location:Apical cell membrane, Membrane, Multi-pass membrane protein
Calculated MW:26kDa/54kDa
Observed MW:65kDa
Synonyms:SLC2A5, GLUT-5, GLUT5
Background:The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption.
UniProt Protein Function:GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: apical plasma membrane; integral to plasma membrane; plasma membrane; sarcolemma

Molecular Function:fructose transmembrane transporter activity; glucose transmembrane transporter activity

Biological Process: carbohydrate metabolic process; fructose transport; glucose transport; hexose transport; regulation of systemic arterial blood pressure mediated by a chemical signal; response to fructose stimulus

UniProt Code:P22732
NCBI GenInfo Identifier:121764
NCBI Gene ID:6518
NCBI Accession:P22732.1
UniProt Secondary Accession:P22732,Q14770, Q5T977, Q8IVB3,
UniProt Related Accession:P22732
Molecular Weight:26,519 Da
NCBI Full Name:Solute carrier family 2, facilitated glucose transporter member 5
NCBI Synonym Full Names:solute carrier family 2 member 5
NCBI Official Symbol:SLC2A5  
NCBI Official Synonym Symbols:GLUT5; GLUT-5  
NCBI Protein Information:solute carrier family 2, facilitated glucose transporter member 5
UniProt Protein Name:Solute carrier family 2, facilitated glucose transporter member 5
UniProt Synonym Protein Names:Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
UniProt Gene Name:SLC2A5  
UniProt Entry Name:GTR5_HUMAN
Anti-SLC2A5 Antibody (CAB13650)Western blot analysis of extracts of various cell lines, using SLC2A5 antibody (CAB13650) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 20s.
View AllClose

0 Reviews

View AllClose

Related Products