Signal Transduction Antibodies 3
Anti-SLC2A3 Antibody (CAB8150)
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- SKU:
- CAB8150
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
| Antibody Name: | SLC2A3 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8150 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC2A3 (NP_008862.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, HepG2, U-87MG |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC2A3 (NP_008862.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LRGA FGTL NQLG IVVG ILVA QIFG LEFI LGSE ELWP LLLG FTIL PAIL QSAA LPFC PESP RFLL INRK EEEN AKQI LQRL WGTQ DVSQ DIQE MKDE SARM S |
| Gene ID: | 6515 |
| Uniprot: | P11169 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 53kDa |
| Observed MW: | 53kDa |
| Synonyms: | SLC2A3, GLUT3 |
| Background: |
| UniProt Protein Function: | GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.3 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose binding; glucose transmembrane transporter activity Biological Process: glucose transport; L-ascorbic acid metabolic process |
| UniProt Code: | P11169 |
| NCBI GenInfo Identifier: | 121760 |
| NCBI Gene ID: | 6515 |
| NCBI Accession: | P11169.1 |
| UniProt Secondary Accession: | P11169,Q6I9U2, Q9UG15, B2R606, D3DUU6, |
| UniProt Related Accession: | P11169 |
| Molecular Weight: | 53924 Da |
| NCBI Full Name: | Solute carrier family 2, facilitated glucose transporter member 3 |
| NCBI Synonym Full Names: | solute carrier family 2 member 3 |
| NCBI Official Symbol: | SLC2A3 |
| NCBI Official Synonym Symbols: | GLUT3 |
| NCBI Protein Information: | solute carrier family 2, facilitated glucose transporter member 3 |
| UniProt Protein Name: | Solute carrier family 2, facilitated glucose transporter member 3 |
| UniProt Synonym Protein Names: | Glucose transporter type 3, brain; GLUT-3 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC2A3 |
| UniProt Entry Name: | GTR3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC2A3 Antibody (CAB8150) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse heart using SLC2A3 antibody (CAB8150) (40x lens). |
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