Metabolism Antibodies 1
Anti-SLC27A1 Antibody (CAB12847)
(No reviews yet)
Write a Review
- SKU:
- CAB12847
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-SLC27A1 Antibody |
| Antibody SKU: | CAB12847 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U2OS, MCF-7, Mouse skeletal muscle, Mouse heart, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QPVR EAER RHRV RLAV GNGL RPAI WEEF TERF GVRQ IGEF YGAT ECNC SIAN MDGK VGSC GFNS RILP HVYP IRLV KVNE DTME LLRD AQGL CIPC QAGE PGLL VGQI NQQD PLRR FDGY VSES ATSK KIAH SVFS KGDS AYLS GDVL VMDE LGYM YFRD RSGD TFRW RGEN VSTT EVEG VLSR LLGQ TDVA VYGV AVPG VEGK AGMA AVAD PHSL LDPN AIYQ ELQK VLAP YARP IFLR LLPQ VDTT GTFK IQKT RLQR EGFD PRQT SDRL FFLD LKQG HYLP LNEA VYTR ICSG AFAL |
| Gene ID: | 376497 |
| Uniprot: | Q6PCB7 |
| Cellular Location: | Cell membrane, Cytoplasm, Endomembrane system, Single-pass membrane protein |
| Calculated MW: | 51kDa/71kDa |
| Observed MW: | 71kDa |
| Synonyms: | SLC27A1, ACSVL5, FATP, FATP-1, FATP1 |
| Background: |
| UniProt Protein Function: | SLC27A1: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family. |
| UniProt Protein Details: | Protein type:EC 6.2.1.-; Ligase; Lipid-binding; Membrane protein, integral; Mitochondrial; Vesicle Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: membrane; plasma membrane Molecular Function:fatty acid transporter activity Biological Process: cardiolipin biosynthetic process; long-chain fatty acid transport; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol biosynthetic process; phosphatidylserine biosynthetic process |
| UniProt Code: | Q6PCB7 |
| NCBI GenInfo Identifier: | 38524616 |
| NCBI Gene ID: | 376497 |
| NCBI Accession: | NP_940982.1 |
| UniProt Secondary Accession: | Q6PCB7,A6NIH2, B7Z662, |
| UniProt Related Accession: | Q6PCB7 |
| Molecular Weight: | |
| NCBI Full Name: | long-chain fatty acid transport protein 1 |
| NCBI Synonym Full Names: | solute carrier family 27 member 1 |
| NCBI Official Symbol: | SLC27A1 |
| NCBI Official Synonym Symbols: | FATP; FATP1; ACSVL5; FATP-1 |
| NCBI Protein Information: | long-chain fatty acid transport protein 1 |
| UniProt Protein Name: | Long-chain fatty acid transport protein 1 |
| UniProt Synonym Protein Names: | Solute carrier family 27 member 1 |
| UniProt Gene Name: | SLC27A1 |
| UniProt Entry Name: | S27A1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC27A1 antibody (CAB12847) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a
