Signal Transduction Antibodies 1
Anti-SLC26A6 Antibody (CAB10323)
- SKU:
- CAB10323
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC26A6 Antibody |
| Antibody SKU: | CAB10323 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 509-758 of human SLC26A6 (NP_599025.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 509-758 of human SLC26A6 (NP_599025.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QMPH YSVL GQVP DTDI YRDV AEYS EAKE VRGV KVFR SSAT VYFA NAEF YSDA LKQR CGVD VDFL ISQK KKLL KKQE QLKL KQLQ KEEK LRKQ AASP KGAS VSIN VNTS LEDM RSNN VEDC KMMV SSGD KMED ATAN GQED SKAP DGST LKAL GLPQ PDFH SLIL DLGA LSFV DTVC LKSL KNIF HDFR EIEV EVYM AACH SPVV SQLE AGHF FDAS ITKK HLFA SVHD AVTF ALQH PRPV PDSP VSVT RL |
| Gene ID: | 65010 |
| Uniprot: | Q9BXS9 |
| Cellular Location: | Apical cell membrane, Basolateral cell membrane, Cell membrane, Cytoplasmic vesicle membrane, Membrane, Microsome, Multi-pass membrane protein |
| Calculated MW: | 73kDa/76kDa/79kDa/80kDa/82kDa |
| Observed MW: | 110kDa |
| Synonyms: | SLC26A6 |
| Background: | This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| UniProt Protein Function: | SLC26A6: Does not seem to be involved in anion transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; integral to membrane; integral to plasma membrane; membrane; plasma membrane; vesicle; vesicle membrane Molecular Function:anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; efflux transmembrane transporter activity; formate efflux transmembrane transporter activity; formate transmembrane transporter activity; formate uptake transmembrane transporter activity; inorganic anion exchanger activity; oxalate transmembrane transporter activity; PDZ domain binding; sulfate transmembrane transporter activity Biological Process: bicarbonate transport; chloride transport; epithelial fluid transport; formate transport; intestinal absorption; intracellular pH elevation; ion transport; mannitol transport; oxalate transport; oxalic acid secretion; regulation of intracellular pH; regulation of membrane potential; sperm capacitation; sulfate transport; transepithelial chloride transport |
| NCBI Summary: | This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q9BXS9 |
| NCBI GenInfo Identifier: | 20140224 |
| NCBI Gene ID: | 65010 |
| NCBI Accession: | Q9BXS9.1 |
| UniProt Secondary Accession: | Q9BXS9,Q548A7, Q96Q90, Q9NQU1, B4DMZ1, |
| UniProt Related Accession: | Q9BXS9 |
| Molecular Weight: | 83kDa |
| NCBI Full Name: | Solute carrier family 26 member 6 |
| NCBI Synonym Full Names: | solute carrier family 26 member 6 |
| NCBI Official Symbol: | SLC26A6 |
| NCBI Protein Information: | solute carrier family 26 member 6 |
| UniProt Protein Name: | Solute carrier family 26 member 6 |
| UniProt Synonym Protein Names: | Anion exchange transporter; Pendrin-like protein 1; Pendrin-L1 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC26A6 |
 | Western blot analysis of extracts of 293T cells, using SLC26A6 antibody (CAB10323) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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