Metabolism Antibodies 1

Anti-SLC25A39 Antibody (CAB15450)

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SKU:
CAB15450
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-SLC25A39 Antibody
Antibody SKU:CAB15450
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 170-250 of human SLC25A39 (NP_057100.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, Mouse spleen, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 170-250 of human SLC25A39 (NP_057100.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VISP LELM RTKL QAQH VSYR ELGA CVRT AVAQ GGWR SLWL GWGP TALR DVPF SALY WFNY ELVK SWLN GFRP KDQT SVGM S
Gene ID:51629
Uniprot:Q9BZJ4
Cellular Location:Mitochondrion inner membrane, Multi-pass membrane protein
Calculated MW:38kDa/39kDa
Observed MW:39kDa
Synonyms:SLC25A39, CGI-69, CGI69
Background:This gene encodes a member of the SLC25 transporter or mitochondrial carrier family of proteins. Members of this family are encoded by the nuclear genome while their protein products are usually embedded in the inner mitochondrial membrane and exhibit wide-ranging substrate specificity. Although the encoded protein is currently considered an orphan transporter, this protein is related to other carriers known to transport amino acids. This protein may play a role in iron homeostasis.
UniProt Protein Function:SLC25A39: Required for normal heme biosynthesis. Belongs to the mitochondrial carrier family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Transporter, SLC family; Mitochondrial; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: mitochondrial inner membrane; integral to membrane

Biological Process: transport; heme biosynthetic process

NCBI Summary:SLC25A39 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
UniProt Code:Q9BZJ4
NCBI GenInfo Identifier:66911248
NCBI Gene ID:51629
NCBI Accession:AAH96819.1
UniProt Secondary Accession:Q9BZJ4,Q4V9M1, Q9P182, Q9UF66, Q9Y379, A8JZZ2, D3DX51 D3DX54,
UniProt Related Accession:Q9BZJ4
Molecular Weight:39 kDa (MW of target protein)
NCBI Full Name:SLC25A39 protein
NCBI Synonym Full Names:solute carrier family 25, member 39
NCBI Official Symbol:SLC25A39  
NCBI Official Synonym Symbols:CGI69; CGI-69  
NCBI Protein Information:solute carrier family 25 member 39
UniProt Protein Name:Solute carrier family 25 member 39
Protein Family:Solute carrier family
UniProt Gene Name:SLC25A39  
UniProt Entry Name:S2539_HUMAN
Anti-SLC25A39 Antibody (CAB15450)Western blot analysis of extracts of various cell lines, using SLC25A39 antibody (CAB15450) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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