Name: Anti-SLC25A17 Antibody (CAB14840)
Brand: Signal Transduction Antibodies 1
SKU: CAB14840
Availability: OutOfStock

Antibody Name:	Anti-SLC25A17 Antibody
Antibody SKU:	CAB14840
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC25A17 (NP_006349.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	Mouse liver, Mouse kidney

Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC25A17 (NP_006349.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	IDAF HQII RDEG ISAL WNGT FPSL LLVF NPAI QFMF YEGL KRQL LKKR MKLS SLDV FIIG AVAK AIAT TVTY PLQT VQSI LRFG RHRL NPEN RTLG SLRN I
Gene ID:	10478
Uniprot:	O43808
Cellular Location:	Cytoplasm, Multi-pass membrane protein, Peroxisome membrane
Calculated MW:	34kDa
Observed MW:	34kDa

Synonyms:	SLC25A17, PMP34
Background:	This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants.

UniProt Protein Function:	SLC25A17: Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro. Belongs to the mitochondrial carrier family.
UniProt Protein Details:	Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: integral to peroxisomal membrane; intracellular membrane-bound organelle; membrane; peroxisomal membrane; peroxisome Molecular Function:adenine nucleotide transmembrane transporter activity; ADP transmembrane transporter activity; ATP transmembrane transporter activity; chaperone binding; coenzyme A transmembrane transporter activity; FAD transmembrane transporter activity; NAD transporter activity; protein binding; structural constituent of ribosome Biological Process: ATP transport; fatty acid alpha-oxidation; fatty acid beta-oxidation; fatty acid transport; translation
NCBI Summary:	This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:	O43808
NCBI GenInfo Identifier:	12643354
NCBI Gene ID:	10478
NCBI Accession:	O43808.1
UniProt Secondary Accession:	O43808,Q5TFL0, Q9UGW8, Q9UGY7, A8KA59,
UniProt Related Accession:	O43808
Molecular Weight:	34,567 Da
NCBI Full Name:	Peroxisomal membrane protein PMP34
NCBI Synonym Full Names:	solute carrier family 25 member 17
NCBI Official Symbol:	SLC25A17
NCBI Official Synonym Symbols:	PMP34
NCBI Protein Information:	peroxisomal membrane protein PMP34
UniProt Protein Name:	Peroxisomal membrane protein PMP34
UniProt Synonym Protein Names:	34 kDa peroxisomal membrane protein; Solute carrier family 25 member 17
Protein Family:	Peroxisomal membrane protein
UniProt Gene Name:	SLC25A17
UniProt Entry Name:	PM34_HUMAN

	Western blot analysis of extracts of various cell lines, using SLC25A17 Rabbit pAb (CAB14840) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunofluorescence analysis of 293T cells using SLC25A17 antibody (CAB14840) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.