Signal Transduction Antibodies 2

Anti-SLC24A4 Antibody (CAB17254)

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SKU:
CAB17254
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC24A4 Antibody
Antibody SKU:CAB17254
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human SLC24A4.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:A synthetic peptide of human SLC24A4.
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:123041
Uniprot:Q8NFF2
Cellular Location:
Calculated MW:52kDa/61kDa/67kDa/69kDa
Observed MW:Refer to figures
Synonyms:SLC24A4, AI2A5, NCKX4, SHEP6, SLC24A2
Background:This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:SLC24A4: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 14q32.12

Cellular Component: cytoplasm; integral to plasma membrane; membrane; plasma membrane

Molecular Function:calcium channel activity; calcium ion binding; calcium, potassium:sodium antiporter activity; potassium ion binding; sodium ion binding

Biological Process: cellular calcium ion homeostasis; ion transport; sensory perception of smell

Disease: Skin/hair/eye Pigmentation, Variation In, 6

NCBI Summary:This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
UniProt Code:Q8NFF2
NCBI GenInfo Identifier:341941166
NCBI Gene ID:123041
NCBI Accession:Q8NFF2.2
UniProt Secondary Accession:Q8NFF2,Q8N8U6, Q8NCX1, Q8NFF0, Q8NFF1, B4DHE7, B9ZVY2
UniProt Related Accession:Q8NFF2
Molecular Weight:52,760 Da
NCBI Full Name:Sodium/potassium/calcium exchanger 4
NCBI Synonym Full Names:solute carrier family 24 member 4
NCBI Official Symbol:SLC24A4  
NCBI Official Synonym Symbols:AI2A5; NCKX4; SHEP6; SLC24A2  
NCBI Protein Information:sodium/potassium/calcium exchanger 4
UniProt Protein Name:Sodium/potassium/calcium exchanger 4
UniProt Synonym Protein Names:Na(+)/K(+)/Ca(2+)-exchange protein 4; Solute carrier family 24 member 4
Protein Family:Sodium/potassium/calcium exchanger
UniProt Gene Name:SLC24A4  
UniProt Entry Name:NCKX4_HUMAN
Anti-SLC24A4 Antibody (CAB17254)Western blot analysis of extracts of various cell lines, using SLC24A4 antibody (CAB17254) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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