Anti-SLC22A3/OCT3 Antibody (CAB19758)
- SKU:
- CAB19758
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EMT
- Synonyms:
- EMTH
- Synonyms:
- OCT3
- Research Area:
- Cell Biology
Description
| Product Name: | SLC22A3/OCT3 Rabbit mAb |
| Product Code: | CAB19758 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | EMT, EMTH, OCT3 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SLC22A3/OCT3 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | PC-3, Mouse liver |
| Immunogen: | A synthesized peptide derived from human SLC22A3/OCT3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6581 |
| Uniprot: | O75751 |
| Calculated MW: | 75kDa |
| Observed MW: | 61KDa |
| UniProt Protein Function: | SLC22A3: Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; toxin transporter activity; organic cation transmembrane transporter activity; dopamine transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity Biological Process: dopamine transport; organic cation transport; histamine uptake; quaternary ammonium group transport; regulation of appetite; multidrug transport; transmembrane transport |
| NCBI Summary: | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75751 |
| NCBI GenInfo Identifier: | 11415038 |
| NCBI Gene ID: | 6581 |
| NCBI Accession: | NP_068812.1 |
| UniProt Related Accession: | O75751 |
| Molecular Weight: | |
| NCBI Full Name: | solute carrier family 22 member 3 |
| NCBI Synonym Full Names: | solute carrier family 22 member 3 |
| NCBI Official Symbol: | SLC22A3 |
| NCBI Official Synonym Symbols: | EMT; EMTH; OCT3 |
| NCBI Protein Information: | solute carrier family 22 member 3 |
| UniProt Protein Name: | Solute carrier family 22 member 3 |
| UniProt Synonym Protein Names: | Extraneuronal monoamine transporter; EMT; Organic cation transporter 3 |
| UniProt Gene Name: | SLC22A3 |
| UniProt Entry Name: | S22A3_HUMAN |
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