Cell Biology Antibodies 15
Anti-SLC22A3 Antibody (CAB18588)
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- SKU:
- CAB18588
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SLC22A3 Antibody |
| Antibody SKU: | CAB18588 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SLC22A3. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant protein of human SLC22A3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6581 |
| Uniprot: | O75751 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 61kDa |
 | Western blot - SLC22A3 Rabbit pAb (CAB18588) |
| Synonyms: | EMT, EMTH, OCT3, SLC22A3 |
| Background: |
| UniProt Protein Function: | SLC22A3: Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; toxin transporter activity; organic cation transmembrane transporter activity; dopamine transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity Biological Process: dopamine transport; organic cation transport; histamine uptake; quaternary ammonium group transport; regulation of appetite; multidrug transport; transmembrane transport |
| NCBI Summary: | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75751 |
| NCBI GenInfo Identifier: | 11415038 |
| NCBI Gene ID: | 6581 |
| NCBI Accession: | NP_068812.1 |
| UniProt Related Accession: | O75751 |
| Molecular Weight: | |
| NCBI Full Name: | solute carrier family 22 member 3 |
| NCBI Synonym Full Names: | solute carrier family 22 member 3 |
| NCBI Official Symbol: | SLC22A3 |
| NCBI Official Synonym Symbols: | EMT; EMTH; OCT3 |
| NCBI Protein Information: | solute carrier family 22 member 3 |
| UniProt Protein Name: | Solute carrier family 22 member 3 |
| UniProt Synonym Protein Names: | Extraneuronal monoamine transporter; EMT; Organic cation transporter 3 |
| UniProt Gene Name: | SLC22A3 |
| UniProt Entry Name: | S22A3_HUMAN |
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