Signal Transduction Antibodies 1
Anti-SLC22A15 Antibody (CAB14408)
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- SKU:
- CAB14408
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC22A15 Antibody |
| Antibody SKU: | CAB14408 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 443-547 of human SLC22A15 (NP_060890.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-87MG, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 443-547 of human SLC22A15 (NP_060890.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RVGG IIAP FIPS LKYV QWSL PFIV FGAT GLTS GLLS LLLP ETLN SPLL ETFS DLQV YSYR RLGE EALS LQAL DPQQ CVDK ESSL GSES EEEE EFYD ADEE TQMI K |
| Gene ID: | 55356 |
| Uniprot: | Q8IZD6 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 26kDa/60kDa |
| Observed MW: | 60kDa |
| Synonyms: | SLC22A15, FLIPT1, PRO34686 |
| Background: |
| UniProt Protein Function: | SLC22A15: Probably transports organic cations. Appears not to be the agmatine transporter. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 1p13.1 Cellular Component: integral to membrane Molecular Function:transmembrane transporter activity Biological Process: ion transport; transmembrane transport |
| NCBI Summary: | Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q8IZD6 |
| NCBI GenInfo Identifier: | 166197673 |
| NCBI Gene ID: | 55356 |
| NCBI Accession: | NP_060890.2 |
| UniProt Secondary Accession: | Q8IZD6,Q6UXP5, Q8TAL9, Q9NSH5, A8MUR3, |
| UniProt Related Accession: | Q8IZD6 |
| Molecular Weight: | 60,540 Da |
| NCBI Full Name: | solute carrier family 22 member 15 |
| NCBI Synonym Full Names: | solute carrier family 22, member 15 |
| NCBI Official Symbol: | SLC22A15 |
| NCBI Official Synonym Symbols: | FLIPT1; PRO34686 |
| NCBI Protein Information: | solute carrier family 22 member 15; flipt 1; trans-like protein; fly-like putative transporter 1; fly-like putative organic ion transporter 1; solute carrier family 22 (organic cation transporter), member 15 |
| UniProt Protein Name: | Solute carrier family 22 member 15 |
| UniProt Synonym Protein Names: | Fly-like putative transporter 1; Flipt 1 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC22A15 |
| UniProt Entry Name: | S22AF_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC22A15 antibody (CAB14408) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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