Signal Transduction Antibodies 2

Anti-SLC17A6 Antibody (CAB15177)

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SKU:
CAB15177
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC17A6 Antibody
Antibody SKU:CAB15177
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC17A6 (NP_065079.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3, SH-SY5Y, U-251MG
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC17A6 (NP_065079.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GEKQ PWAD PEET SEEK CGFI HEDE LDEE TGDI TQNY INYG TTKS YGAT TQAN GGWP SGWE KKEE FVQG EVQD SHSY KDRV DYS
Gene ID:57084
Uniprot:Q9P2U8
Cellular Location:Cell junction, Cytoplasmic vesicle, Membrane, Multi-pass membrane protein, secretory vesicle, synapse, synaptic vesicle membrane, synaptosome
Calculated MW:64kDa
Observed MW:64KDa
Synonyms:SLC17A6, DNPI, VGLUT2
Background:
UniProt Protein Function:SLC17A6: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
UniProt Protein Details:

Protein type:Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 11p14.3

Cellular Component: neuron projection; synaptic vesicle membrane; integral to membrane; cell junction

Molecular Function:symporter activity; L-glutamate transmembrane transporter activity

Biological Process: sodium ion transport; neurotransmitter uptake; ion transport; transmembrane transport

UniProt Code:Q9P2U8
NCBI GenInfo Identifier:9966811
NCBI Gene ID:57084
NCBI Accession:NP_065079.1
UniProt Related Accession:Q9P2U8
Molecular Weight:
NCBI Full Name:vesicular glutamate transporter 2
NCBI Synonym Full Names:solute carrier family 17 member 6
NCBI Official Symbol:SLC17A6  
NCBI Official Synonym Symbols:DNPI; VGLUT2  
NCBI Protein Information:vesicular glutamate transporter 2
UniProt Protein Name:Vesicular glutamate transporter 2
UniProt Synonym Protein Names:Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 6
UniProt Gene Name:SLC17A6  
UniProt Entry Name:VGLU2_HUMAN
Anti-SLC17A6 Antibody (CAB15177)Western blot analysis of extracts of various cell lines, using SLC17A6 Polyclonal Antibody (CAB15177) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-SLC17A6 Antibody (CAB15177)Immunofluorescence analysis of rat brain using SLC17A6 Rabbit pAb (CAB15177) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Anti-SLC17A6 Antibody (CAB15177)Immunofluorescence analysis of mouse brain using SLC17A6 Rabbit pAb (CAB15177) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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