Signal Transduction Antibodies 1

Anti-SLC16A4 Antibody (CAB14818)

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SKU:
CAB14818
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC16A4 Antibody
Antibody SKU:CAB14818
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC16A4 (NP_004687.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:SW480
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC16A4 (NP_004687.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KNLT VSQN QSEE FYNG PNRN RLLL KSDE ESDK VISW SCKQ LFDI SLFR NPFF YIFT WSFL LSQL AYFI PTFH LVAR AKTL GIDI MDAS YLVS VAGI LETV S
Gene ID:9122
Uniprot:O15374
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:35kDa/42kDa/46kDa/49kDa/54kDa
Observed MW:60kDa
Synonyms:SLC16A4, MCT4, MCT5
Background:
UniProt Protein Function:SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: membrane; integral to plasma membrane; integral to membrane

Molecular Function:monocarboxylic acid transmembrane transporter activity; symporter activity

Biological Process: monocarboxylic acid transport

UniProt Code:O15374
NCBI GenInfo Identifier:6225706
NCBI Gene ID:9122
NCBI Accession:O15374.1
UniProt Related Accession:O15374
Molecular Weight:
NCBI Full Name:Monocarboxylate transporter 5
NCBI Synonym Full Names:solute carrier family 16 member 4
NCBI Official Symbol:SLC16A4  
NCBI Official Synonym Symbols:MCT4; MCT5  
NCBI Protein Information:monocarboxylate transporter 5
UniProt Protein Name:Monocarboxylate transporter 5
UniProt Synonym Protein Names:Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 4
UniProt Gene Name:SLC16A4  
UniProt Entry Name:MOT5_HUMAN
Anti-SLC16A4 Antibody (CAB14818)Western blot analysis of extracts of SW480 cells, using SLC16A4 Rabbit pAb (CAB14818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-SLC16A4 Antibody (CAB14818)Immunohistochemistry of paraffin-embedded human liver using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens).
Anti-SLC16A4 Antibody (CAB14818)Immunohistochemistry of paraffin-embedded human liver cancer using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens).
Anti-SLC16A4 Antibody (CAB14818)Immunohistochemistry of paraffin-embedded human gastric cancer using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens).
Anti-SLC16A4 Antibody (CAB14818)Immunofluorescence analysis of HeLa cells using SLC16A4 antibody (CAB14818) at dilution of 1:100. Blue: DAPI for nuclear staining.
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