Signal Transduction Antibodies 1
Anti-SLC16A4 Antibody (CAB14818)
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- SKU:
- CAB14818
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC16A4 Antibody |
| Antibody SKU: | CAB14818 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC16A4 (NP_004687.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | SW480 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC16A4 (NP_004687.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KNLT VSQN QSEE FYNG PNRN RLLL KSDE ESDK VISW SCKQ LFDI SLFR NPFF YIFT WSFL LSQL AYFI PTFH LVAR AKTL GIDI MDAS YLVS VAGI LETV S |
| Gene ID: | 9122 |
| Uniprot: | O15374 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 35kDa/42kDa/46kDa/49kDa/54kDa |
| Observed MW: | 60kDa |
| Synonyms: | SLC16A4, MCT4, MCT5 |
| Background: |
| UniProt Protein Function: | SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p13.3 Cellular Component: membrane; integral to plasma membrane; integral to membrane Molecular Function:monocarboxylic acid transmembrane transporter activity; symporter activity Biological Process: monocarboxylic acid transport |
| UniProt Code: | O15374 |
| NCBI GenInfo Identifier: | 6225706 |
| NCBI Gene ID: | 9122 |
| NCBI Accession: | O15374.1 |
| UniProt Related Accession: | O15374 |
| Molecular Weight: | |
| NCBI Full Name: | Monocarboxylate transporter 5 |
| NCBI Synonym Full Names: | solute carrier family 16 member 4 |
| NCBI Official Symbol: | SLC16A4 |
| NCBI Official Synonym Symbols: | MCT4; MCT5 |
| NCBI Protein Information: | monocarboxylate transporter 5 |
| UniProt Protein Name: | Monocarboxylate transporter 5 |
| UniProt Synonym Protein Names: | Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 4 |
| UniProt Gene Name: | SLC16A4 |
| UniProt Entry Name: | MOT5_HUMAN |
 | Western blot analysis of extracts of SW480 cells, using SLC16A4 Rabbit pAb (CAB14818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human liver using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver cancer using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using SLC16A4 antibody (CAB14818) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of HeLa cells using SLC16A4 antibody (CAB14818) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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