| UniProt Protein Function: | SLC15A2: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Belongs to the PTR2/POT transporter (TC 2.A.17) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 3q13.33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function: high affinity oligopeptide transporter activity; protein binding; antibiotic transporter activity; peptide:hydrogen symporter activity; dipeptide transporter activity Biological Process: protein transport; proton transport; drug transport; transport; antibiotic transport; ion transport; transmembrane transport; dipeptide transport |
| UniProt Protein Details: | |
| NCBI Summary: | The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).[supplied by OMIM, Feb 2011] |
| UniProt Code: | Q16348 |
| NCBI GenInfo Identifier: | 226371748 |
| NCBI Gene ID: | 6565 |
| NCBI Accession: | NP_066568 |
| UniProt Secondary Accession: | Q16348,A8K1A5, B4E2A7 |
| UniProt Related Accession: | Q16348 |
| Molecular Weight: | |
| NCBI Full Name: | solute carrier family 15 member 2 isoform b |
| NCBI Synonym Full Names: | solute carrier family 15 (oligopeptide transporter), member 2 |
| NCBI Official Symbol: | SLC15A2 |
| NCBI Official Synonym Symbols: | PEPT2 |
| NCBI Protein Information: | solute carrier family 15 member 2 |
| UniProt Protein Name: | Solute carrier family 15 member 2 |
| UniProt Synonym Protein Names: | Kidney H(+)/peptide cotransporter; Oligopeptide transporter, kidney isoform; Peptide transporter 2 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC15A2 |
| UniProt Entry Name: | S15A2_HUMAN |
