Immunology Antibodies 2

Anti-SLAMF7 Antibody (CAB5782)

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SKU:
CAB5782
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SLAMF7 Antibody
Antibody SKU:CAB5782
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-226 of human SLAMF7 (NP_067004.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:THP-1, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-226 of human SLAMF7 (NP_067004.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SGPV KELV GSVG GAVT FPLK SKVK QVDS IVWT FNTT PLVT IQPE GGTI IVTQ NRNR ERVD FPDG GYSL KLSK LKKN DSGI YYVG IYSS SLQQ PSTQ EYVL HVYE HLSK PKVT MGLQ SNKN GTCV TNLT CCME HGEE DVIY TWKA LGQA ANES HNGS ILPI SWRW GESD MTFI CVAR NPVS RNFS SPIL ARKL CEGA ADDP DSSM
Gene ID:57823
Uniprot:Q9NQ25
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:17kDa/21kDa/22kDa/25kDa/32kDa/37kDa
Observed MW:25-80KDa
Synonyms:SLAMF7, 19A, CD319, CRACC, CS1
Background:
UniProt Protein Function:SLAMF7: Isoform 1 mediates NK cell activation through a SH2D1A- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1-q24.1

Cellular Component: plasma membrane

Biological Process: regulation of immune response

UniProt Code:Q9NQ25
NCBI GenInfo Identifier:19923572
NCBI Gene ID:57823
NCBI Accession:NP_067004.3
UniProt Secondary Accession:Q9NQ25,Q8N6Y8, Q8ND32, Q9NY08, Q9NY23, A8K3U1, B4DPU4 B4DPY3, B4DWA3,
UniProt Related Accession:Q9NQ25
Molecular Weight:
NCBI Full Name:SLAM family member 7 isoform a
NCBI Synonym Full Names:SLAM family member 7
NCBI Official Symbol:SLAMF7  
NCBI Official Synonym Symbols:19A; CS1; CD319; CRACC  
NCBI Protein Information:SLAM family member 7; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein
UniProt Protein Name:SLAM family member 7
UniProt Synonym Protein Names:CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD_antigen: CD319
Protein Family:SLAM family
UniProt Gene Name:SLAMF7  
UniProt Entry Name:SLAF7_HUMAN
Anti-SLAMF7 Antibody (CAB5782)Western blot analysis of extracts of various cell lines, using SLAMF7 antibody (CAB5782) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-SLAMF7 Antibody (CAB5782)Immunofluorescence analysis of human spleen using SLAMF7 Polyclonal Antibody (CAB5782) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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system_update_altDatasheetHuman SLAMF7/CD319 Recombinant Protein SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed i