Immunology Antibodies 1
Anti-SLAMF7 Antibody (CAB14144)
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- SKU:
- CAB14144
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-SLAMF7 Antibody |
| Antibody SKU: | CAB14144 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-226 of human SLAMF7 (NP_067004.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Raji, K-562, Mouse testis, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-226 of human SLAMF7 (NP_067004.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SGPV KELV GSVG GAVT FPLK SKVK QVDS IVWT FNTT PLVT IQPE GGTI IVTQ NRNR ERVD FPDG GYSL KLSK LKKN DSGI YYVG IYSS SLQQ PSTQ EYVL HVYE HLSK PKVT MGLQ SNKN GTCV TNLT CCME HGEE DVIY TWKA LGQA ANES HNGS ILPI SWRW GESD MTFI CVAR NPVS RNFS SPIL ARKL CEGA ADDP DSSM |
| Gene ID: | 57823 |
| Uniprot: | Q9NQ25 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 17kDa/21kDa/22kDa/25kDa/32kDa/37kDa |
| Observed MW: | 25-70KDa |
| Synonyms: | SLAMF7, 19A, CD319, CRACC, CS1 |
| Background: |
| UniProt Protein Function: | SLAMF7: Isoform 1 mediates NK cell activation through a SH2D1A- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q23.1-q24.1 Cellular Component: plasma membrane Biological Process: regulation of immune response |
| UniProt Code: | Q9NQ25 |
| NCBI GenInfo Identifier: | 19923572 |
| NCBI Gene ID: | 57823 |
| NCBI Accession: | NP_067004.3 |
| UniProt Secondary Accession: | Q9NQ25,Q8N6Y8, Q8ND32, Q9NY08, Q9NY23, A8K3U1, B4DPU4 B4DPY3, B4DWA3, |
| UniProt Related Accession: | Q9NQ25 |
| Molecular Weight: | |
| NCBI Full Name: | SLAM family member 7 isoform a |
| NCBI Synonym Full Names: | SLAM family member 7 |
| NCBI Official Symbol: | SLAMF7 |
| NCBI Official Synonym Symbols: | 19A; CS1; CD319; CRACC |
| NCBI Protein Information: | SLAM family member 7; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein |
| UniProt Protein Name: | SLAM family member 7 |
| UniProt Synonym Protein Names: | CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD_antigen: CD319 |
| Protein Family: | SLAM family |
| UniProt Gene Name: | SLAMF7 |
| UniProt Entry Name: | SLAF7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLAMF7 antibody (CAB14144) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunofluorescence analysis of U2OS cells using SLAMF7 antibody (CAB14144). Blue: DAPI for nuclear staining. |
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