Cell Biology Antibodies 14
Anti-SIX6 Antibody (CAB18167)
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- SKU:
- CAB18167
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SIX6 Antibody |
| Antibody SKU: | CAB18167 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SIX6. |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human SIX6. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4990 |
| Uniprot: | O95475 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | MCOPCT2, ODRMD, OPTX2, Six9, SIX6 |
| Background: |
| UniProt Protein Function: | SIX6: May be involved in eye development. Defects in SIX6 are the cause of microphthalmia isolated with cataract type 2 (MCOPCT2). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present. Belongs to the SIX/Sine oculis homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 14q23.1 Biological Process: organ morphogenesis; visual perception Disease: Microphthalmia, Isolated, With Cataract 2; Microphthalmia, Syndromic 3 |
| NCBI Summary: | The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2). [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95475 |
| NCBI GenInfo Identifier: | 115502450 |
| NCBI Gene ID: | 4990 |
| NCBI Accession: | O95475.2 |
| UniProt Secondary Accession: | O95475,Q6NT42, Q9P1X8, |
| UniProt Related Accession: | O95475 |
| Molecular Weight: | 27,687 Da |
| NCBI Full Name: | Homeobox protein SIX6 |
| NCBI Synonym Full Names: | SIX homeobox 6 |
| NCBI Official Symbol: | SIX6 |
| NCBI Official Synonym Symbols: | Six9; ODRMD; OPTX2; MCOPCT2 |
| NCBI Protein Information: | homeobox protein SIX6 |
| UniProt Protein Name: | Homeobox protein SIX6 |
| UniProt Synonym Protein Names: | Homeodomain protein OPTX2; Optic homeobox 2; Sine oculis homeobox homolog 6 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | SIX6 |
| UniProt Entry Name: | SIX6_HUMAN |
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