Cell Biology Antibodies 14
Anti-SIX4 Antibody (CAB14406)
- SKU:
- CAB14406
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-SIX4 Antibody |
Antibody SKU: | CAB14406 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 512-781 of human SIX4 (NP_059116.3). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | 293T, HeLa, Mouse heart |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 512-781 of human SIX4 (NP_059116.3). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | VAAS QGNI SVSS STSD GSTF TSES TTVQ QGKV FLSS LAPS AVVY TVPN TGQT IGSV KQEG LERS LVFS QLMP VNQN AQVN ANLS SENI SGSG LHPL ASSL VNVS PTHN FSLS PSTL LNPT ELNR DIAD SQPM SAPV ASKS TVTS VSNT NYAT LQNC SLIT GQDL LSVP MTQA ALGE IVPT AEDQ VGHP SPAV HQDF VQEH RLVL QSVA NMKE NFLS NSES KATS SLMM LDSK SKYV LDGM VDTV CEDL ETDK KELA KLQT VQLD EDMQ DL |
Gene ID: | 51804 |
Uniprot: | Q9UIU6 |
Cellular Location: | Cytoplasm, Nucleus |
Calculated MW: | 82kDa |
Observed MW: | 83kDa |
Synonyms: | SIX4, AREC3 |
Background: | This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. |
UniProt Protein Function: | SIX4: a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010] |
UniProt Protein Details: | Protein type:Cell development/differentiation; Transcription factor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q23 Cellular Component: cytoplasm; nucleus Molecular Function:sequence-specific DNA binding; transcription factor activity Biological Process: tongue development; anatomical structure morphogenesis; skeletal muscle development; inner ear morphogenesis; pharyngeal system development; transcription, DNA-dependent; thymus development; positive regulation of transcription, DNA-dependent; male gonad development; embryonic cranial skeleton morphogenesis; sarcomere organization; olfactory placode formation; regulation of epithelial cell proliferation; male sex differentiation; regulation of protein localization; generation of neurons; male sex determination; myoblast migration; regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis |
NCBI Summary: | This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010] |
UniProt Code: | Q9UIU6 |
NCBI GenInfo Identifier: | 142976638 |
NCBI Gene ID: | 51804 |
NCBI Accession: | NP_059116 |
UniProt Related Accession: | Q9UIU6 |
Molecular Weight: | 83kDa |
NCBI Full Name: | homeobox protein SIX4 |
NCBI Synonym Full Names: | SIX homeobox 4 |
NCBI Official Symbol: | SIX4 |
NCBI Official Synonym Symbols: | AREC3 |
NCBI Protein Information: | homeobox protein SIX4 |
UniProt Protein Name: | Homeobox protein SIX4 |
UniProt Synonym Protein Names: | Sine oculis homeobox homolog 4 |
Protein Family: | Homeobox protein |
UniProt Gene Name: | SIX4 |
UniProt Entry Name: | SIX4_HUMAN |