Cell Biology Antibodies 13

Anti-SIRT3 Antibody (CAB17113)

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SKU:
CAB17113
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SIRT3 Antibody
Antibody SKU:CAB17113
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human SIRT3 (NP_036371.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human SIRT3 (NP_036371.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ERVE AGGG VGPF QACG CRLV LGGR DDVS AGLR GSHG ARGE PLDP ARPL QRPP RPEV PRAF RRQP RAAA PSFF FSSI KGGR RSIS FSVG ASSV VGSG GSSD KGKL SLQD VAE
Gene ID:23410
Uniprot:Q9NTG7
Cellular Location:Mitochondrion matrix
Calculated MW:28kDa/43kDa
Observed MW:Refer to figures
Anti-SIRT3 Antibody (CAB17113)Immunohistochemistry - SIRT3 Rabbit pAb (CAB17113)
Synonyms:SIRT3, SIR2L3, sirtuin 3
Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
UniProt Code:Q9NTG7
NCBI GenInfo Identifier:38258651
NCBI Gene ID:23410
NCBI Accession:Q9NTG7.2
UniProt Secondary Accession:Q9NTG7,Q9Y6E8, B7Z5U6,
UniProt Related Accession:Q9NTG7
Molecular Weight:399
NCBI Full Name:NAD-dependent protein deacetylase sirtuin-3, mitochondrial
NCBI Synonym Full Names:sirtuin 3
NCBI Official Symbol:SIRT3  
NCBI Official Synonym Symbols:SIR2L3  
NCBI Protein Information:NAD-dependent protein deacetylase sirtuin-3, mitochondrial; sir2-like 3; sirtuin type 3; SIR2-like protein 3; regulatory protein SIR2 homolog 3; NAD-dependent deacetylase sirtuin-3, mitochondrial; silent mating type information regulation 2, S.cerevisiae, homolog 3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
UniProt Protein Name:NAD-dependent protein deacetylase sirtuin-3, mitochondrial
UniProt Synonym Protein Names:Regulatory protein SIR2 homolog 3; SIR2-like protein 3
Protein Family:NAD-dependent protein deacetylase sirtuin
UniProt Gene Name:SIRT3  
UniProt Entry Name:SIR3_HUMAN
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