Cell Biology Antibodies 9
Anti-SIRPG Antibody (CAB4832)
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- SKU:
- CAB4832
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SIRPG
- Synonyms:
- CD172g
- Synonyms:
- SIRP-B2
- Synonyms:
- SIRPB2
- Synonyms:
- SIRPgamma
- Synonyms:
- bA77C3.1
- Research Area:
- Cell Biology
Description
| Product Name: | SIRPG Rabbit pAb |
| Product Code: | CAB4832 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | SIRPG, CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-140 of human SIRPG (NP_543006.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | LO2, A-549, 293T, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-140 of human SIRPG (NP_543006.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IQPE KLLL VTVG KTAT LHCT VTSL LPVG PVLW FRGV GPGR ELIY NQKE GHFP RVTT VSDL TKRN NMDF SIRI SSIT PADV GTYY CVKF RKGS PENV EFKS GPGT EM |
| Gene ID: | 55423 |
| Uniprot: | Q9P1W8 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 18kDa/29kDa/38kDa/42kDa |
| Observed MW: | 45-50kDa |
| UniProt Protein Function: | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| NCBI Summary: | The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9P1W8 |
| NCBI GenInfo Identifier: | 124053651 |
| NCBI Gene ID: | 55423 |
| NCBI Accession: | Q9P1W8.3 |
| UniProt Secondary Accession: | Q9P1W8,Q5D051, Q5JV25, Q5MKL4, Q8WWA5, Q9NQK8, B1AKP6 |
| UniProt Related Accession: | Q9P1W8 |
| Molecular Weight: | 29,967 Da |
| NCBI Full Name: | Signal-regulatory protein gamma |
| NCBI Synonym Full Names: | signal regulatory protein gamma |
| NCBI Official Symbol: | SIRPG |
| NCBI Official Synonym Symbols: | CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma |
| NCBI Protein Information: | signal-regulatory protein gamma |
| UniProt Protein Name: | Signal-regulatory protein gamma |
| UniProt Synonym Protein Names: | CD172 antigen-like family member B; Signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD_antigen: CD172g |
| Protein Family: | Signal-regulatory protein |
| UniProt Gene Name: | SIRPG |
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