Cell Death Antibodies 1

Anti-SIAH2 Antibody (CAB16211)

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SKU:
CAB16211
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SIAH2 Antibody
Antibody SKU:CAB16211
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide of human SIAH2
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:SKOV3
Immunogen:A synthetic peptide of human SIAH2
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6478
Uniprot:O43255
Cellular Location:
Calculated MW:34kDa
Observed MW:35kDa
Synonyms:SIAH2, hSiah2
Background:This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.
NCBI Summary:This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008]
UniProt Code:O43255
NCBI GenInfo Identifier:31982899
NCBI Gene ID:6478
NCBI Accession:NP_005058.3
UniProt Related Accession:O43255
Molecular Weight:34kDa
NCBI Full Name:E3 ubiquitin-protein ligase SIAH2
NCBI Synonym Full Names:siah E3 ubiquitin protein ligase 2
NCBI Official Symbol:SIAH2  
NCBI Official Synonym Symbols:hSiah2  
NCBI Protein Information:E3 ubiquitin-protein ligase SIAH2
UniProt Protein Name:E3 ubiquitin-protein ligase SIAH2
UniProt Synonym Protein Names:Seven in absentia homolog 2; Siah-2; hSiah2
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:SIAH2  
UniProt Entry Name:SIAH2_HUMAN
Anti-SIAH2 Antibody (CAB16211)Western blot analysis of extracts of SKOV3 cells, using SIAH2 antibody (CAB16211) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5min.
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