Cell Biology Antibodies 5
Anti-SH2D3A Antibody (CAB14832)
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- SKU:
- CAB14832
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SH2D3A Antibody |
| Antibody SKU: | CAB14832 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SH2D3A (NP_005481.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | BxPC-3, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SH2D3A (NP_005481.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQVP QDGE DLAG QPWY HGLL SRQK AEAL LQQN GDFL VRAS GSRG GNPV ISCR WRGS ALHF EVFR VALR PRPG RPTA LFQL EDEQ FPSI PALV HSYM TGRR PLSQ ATGA VVSR PVTW QGPL RRSF SEDT LMDG PARI EPLR ARKW SNSQ PADL AHMG RSRE DPAG MEAS TMPI SALP RTSS DPVL LKAP APLG TVAD SLRA SDGQ LQAK APTK PPRT PSFE LPDA SERP PTYC ELVP RVPS VQGT SPSQ SCPE PEAP WWEA EEDE EEEN RCFT RPQA EISF CPHD APSC LLGP QNRP LEPQ |
| Gene ID: | 10045 |
| Uniprot: | Q9BRG2 |
| Cellular Location: | |
| Calculated MW: | 52kDa/63kDa |
| Observed MW: | 63kDa |
| Synonyms: | SH2D3A, NSP1 |
| Background: |
| UniProt Protein Function: | SH2D3A: May play a role in JNK activation. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 19p13.3 Molecular Function:protein binding; SH3/SH2 adaptor activity; guanyl-nucleotide exchange factor activity Biological Process: positive regulation of signal transduction; small GTPase mediated signal transduction; JNK cascade; positive regulation of GTPase activity |
| UniProt Code: | Q9BRG2 |
| NCBI GenInfo Identifier: | 74732879 |
| NCBI Gene ID: | 10045 |
| NCBI Accession: | Q9BRG2.1 |
| UniProt Secondary Accession: | Q9BRG2,Q9Y2X4, A8K9R6, B4DRS7, |
| UniProt Related Accession: | Q9BRG2 |
| Molecular Weight: | 52,402 Da |
| NCBI Full Name: | SH2 domain-containing protein 3A |
| NCBI Synonym Full Names: | SH2 domain containing 3A |
| NCBI Official Symbol: | SH2D3A |
| NCBI Official Synonym Symbols: | NSP1 |
| NCBI Protein Information: | SH2 domain-containing protein 3A; SH2 domain-containing 3A; novel SH2-containing protein 1 |
| UniProt Protein Name: | SH2 domain-containing protein 3A |
| UniProt Synonym Protein Names: | Novel SH2-containing protein 1 |
| Protein Family: | SH2 domain-containing protein |
| UniProt Gene Name: | SH2D3A |
| UniProt Entry Name: | SH23A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SH2D3A antibody (CAB14832) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 180s. |
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