Epigenetics & Nuclear Signaling Antibodies 3
Anti-SF3A3 Antibody (CAB4465)
(No reviews yet)
Write a Review
- SKU:
- CAB4465
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SF3A3
- Synonyms:
- PRP9
- Synonyms:
- PRPF9
- Synonyms:
- SAP61
- Synonyms:
- SF3a60
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | SF3A3 Rabbit pAb |
| Product Code: | CAB4465 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | SF3A3, PRP9, PRPF9, SAP61, SF3a60 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1). |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, NIH/3T3, Raji, Mouse heart, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SLES LDTS LFAK NPKS KGTK RDTE RNKD IAFL EAQI YEYV EILG EQRH LTHE NVQR KQAR TGEE REEE EEEQ ISES ESED EENE IIYN PKNL PLGW DGKP IPYW LYKL HGLN INYN CEIC GNYT YRGP KAFQ RHFA EWRH AHGM RCLG IPNT AHFA NVTQ IEDA VSLW AKLK LQKA SERW QPDT EEEY EDSS GNVV NKKT YEDL KRQG LL |
| Gene ID: | 10946 |
| Uniprot: | Q12874 |
| Cellular Location: | Nucleus speckle |
| Calculated MW: | 58kDa |
| Observed MW: | 59KDa |
| UniProt Protein Function: | SF3A3: subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. |
| UniProt Protein Details: | Protein type:Spliceosome; Motility/polarity/chemotaxis; RNA-binding; RNA splicing Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: nucleoplasm; spliceosome; nuclear speck Molecular Function:protein binding; zinc ion binding Biological Process: nuclear mRNA 3'-splice site recognition; RNA splicing, via transesterification reactions; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA processing |
| NCBI Summary: | This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q12874 |
| NCBI GenInfo Identifier: | 17380310 |
| NCBI Gene ID: | 10946 |
| NCBI Accession: | Q12874.1 |
| UniProt Secondary Accession: | Q12874,Q15460, Q5VT87, D3DPT5, |
| UniProt Related Accession: | Q12874 |
| Molecular Weight: | 501 |
| NCBI Full Name: | Splicing factor 3A subunit 3 |
| NCBI Synonym Full Names: | splicing factor 3a, subunit 3, 60kDa |
| NCBI Official Symbol: | SF3A3 |
| NCBI Official Synonym Symbols: | PRP9; PRPF9; SAP61; SF3a60 |
| NCBI Protein Information: | splicing factor 3A subunit 3; SAP 61; spliceosome associated protein 61; spliceosome-associated protein 61; splicing factor 3a, subunit 3, 60kD; pre-mRNA splicing factor SF3a (60kD) |
| UniProt Protein Name: | Splicing factor 3A subunit 3 |
| UniProt Synonym Protein Names: | SF3a60; Spliceosome-associated protein 61; SAP 61 |
| UniProt Gene Name: | SF3A3 |
| UniProt Entry Name: | SF3A3_HUMAN |
Related Products
Anti-SF3A3 Antibody (CAB20927)
OverviewAntibody Name:Anti-SF3A3 Antibody (CAB20927)Antibody SKU:CAB20927Antibody Size:50µL, 100µLApplication:Western blottingReactivit
Anti-RANBP3 Antibody (CAB0092)
OverviewProduct Name:RANBP3 Rabbit mAbProduct Code:CAB0092Size:20uL, 50uL, 100uLSynonyms:RANBP3, ran-binding protein 3
Anti-QK1 Antibody (CAB0193)
OverviewProduct Name:QK1 Rabbit mAbProduct Code:CAB0193Size:20uL, 50uL, 100uLSynonyms:QKI, Hqk, QK, QK1, QK3, hqkI, protein quaking
Anti-DEK Antibody (CAB0315)
OverviewProduct Name:DEK Rabbit mAbProduct Code:CAB0315Size:20uL, 50uL, 100uLSynonyms:D6S231EApplications:WB,
Anti-EXOSC7 Antibody (CAB0501)
OverviewProduct Name:EXOSC7 Rabbit mAbProduct Code:CAB0501Size:20uL, 50uL, 100uLSynonyms:EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exoso