Epigenetics & Nuclear Signaling Antibodies 4
Anti-SETD5 Antibody (CAB7304)
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- SKU:
- CAB7304
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-SETD5 Antibody |
| Antibody SKU: | CAB7304 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-740 of human SETD5 (NP_001073986.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-740 of human SETD5 (NP_001073986.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HAFE NLEK RKKR RDQP LEQS NSDV EITT TTSE TPVG EETK TEAP ESEV SNSV SNVT IPST PQSV GVNT RRSS QAGD IAAE KLVP KPPP AKPS RPRP KSRI SRYR TSSA QRLK RQKQ ANAQ QAEL SQAA LEEG GSNS LVTP TEAG SLDS SGEN RPLT GSDP TVVS ITGS HVNR AASK YPKT KKYL VTEW LNDK AEKQ ECPV ECPL RITT DPTV LATT LNML P |
| Gene ID: | 55209 |
| Uniprot: | Q9C0A6 |
| Cellular Location: | |
| Calculated MW: | 145kDa/147kDa/157kDa |
| Observed MW: | 158kDa |
| Synonyms: | SETD5 |
| Background: | This function of this gene has yet to be determined but mutations in this gene have been associated with autosomal dominant mental retardation-23. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | SETD5: 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Methyltransferase; Methyltransferase, protein lysine, predicted Chromosomal Location of Human Ortholog: 3p25.3 Disease: Mental Retardation, Autosomal Dominant 23 |
| NCBI Summary: | This function of this gene has yet to be determined but mutations in this gene have been associated with autosomal dominant mental retardation-23. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014] |
| UniProt Code: | Q9C0A6 |
| NCBI GenInfo Identifier: | 143584285 |
| NCBI Gene ID: | 55209 |
| NCBI Accession: | Q9C0A6.2 |
| UniProt Secondary Accession: | Q9C0A6,Q6AI17, Q8WUB6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9 |
| UniProt Related Accession: | Q9C0A6 |
| Molecular Weight: | Calculated: 145kDa/147kDa/157kDaObserved: 158kDa |
| NCBI Full Name: | SET domain-containing protein 5 |
| NCBI Synonym Full Names: | SET domain containing 5 |
| NCBI Official Symbol: | SETD5 |
| NCBI Protein Information: | SET domain-containing protein 5 |
| UniProt Protein Name: | SET domain-containing protein 5 |
| Protein Family: | SET domain-containing protein |
| UniProt Gene Name: | SETD5 |
| UniProt Entry Name: | SETD5_HUMAN |
 | Western blot analysis of extracts of MCF-7 cells, using SETD5 antibody (CAB7304) at 1:300 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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