Epigenetics & Nuclear Signaling Antibodies 4

Anti-SERTAD1 Antibody (CAB8621)

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SKU:
CAB8621

Description

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Antibody Name:Anti-SERTAD1 Antibody
Antibody SKU:CAB8621
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat testis, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MLSK GLKR KREE EEEK EPLA VDSW WLDP GHTA VAQA PPAV ASSS LFDL SVLK LHHS LQQS EPDL RHLV LVVN TLRR IQAS MAPA AALP PVPS PPAA PSVA DNLL ASSD AALS ASMA SLLE DLSH IEGL SQAP QPLA DEGP PGRS IGGA APSL GALD LLGP ATGC LLDD GLEG LFED IDTS MYDN ELWA PASE GLKP GPED GPGK EEAP ELDE AELD YLMD VLVG TQAL ERPP GPGR
Gene ID:29950
Uniprot:Q9UHV2
Cellular Location:
Calculated MW:24kDa
Observed MW:25kDa
Synonyms:SERTAD1, SEI1, TRIP-Br1
Background:
UniProt Protein Function:SERTAD1: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).
UniProt Protein Details:

Protein type:Cell cycle regulation; Transcription regulation

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Molecular Function:protein binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; regulation of cyclin-dependent protein kinase activity

UniProt Code:Q9UHV2
NCBI GenInfo Identifier:153792060
NCBI Gene ID:29950
NCBI Accession:NP_037508.2
UniProt Secondary Accession:Q9UHV2,Q9BUE7,
UniProt Related Accession:Q9UHV2
Molecular Weight:24,704 Da
NCBI Full Name:SERTA domain-containing protein 1
NCBI Synonym Full Names:SERTA domain containing 1
NCBI Official Symbol:SERTAD1  
NCBI Official Synonym Symbols:SEI1; TRIP-Br1  
NCBI Protein Information:SERTA domain-containing protein 1; CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; SEI-1; transcriptional regulator interacting with the PHD-bromodomain 1
UniProt Protein Name:SERTA domain-containing protein 1
UniProt Synonym Protein Names:CDK4-binding protein p34SEI1; SEI-1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP-Br1
UniProt Gene Name:SERTAD1  
UniProt Entry Name:SRTD1_HUMAN
Anti-SERTAD1 Polyclonal Antibody (CAB8621)Western blot analysis of extracts of various cell lines, using SERTAD1 antibody (CAB8621) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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Additional Information

Product Type:
Antibody
Applications:
WB
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
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