Epigenetics & Nuclear Signaling Antibodies 4
Anti-SERTAD1 Antibody (CAB8621)
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- SKU:
- CAB8621
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-SERTAD1 Antibody |
| Antibody SKU: | CAB8621 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat testis, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MLSK GLKR KREE EEEK EPLA VDSW WLDP GHTA VAQA PPAV ASSS LFDL SVLK LHHS LQQS EPDL RHLV LVVN TLRR IQAS MAPA AALP PVPS PPAA PSVA DNLL ASSD AALS ASMA SLLE DLSH IEGL SQAP QPLA DEGP PGRS IGGA APSL GALD LLGP ATGC LLDD GLEG LFED IDTS MYDN ELWA PASE GLKP GPED GPGK EEAP ELDE AELD YLMD VLVG TQAL ERPP GPGR |
| Gene ID: | 29950 |
| Uniprot: | Q9UHV2 |
| Cellular Location: | |
| Calculated MW: | 24kDa |
| Observed MW: | 25kDa |
| Synonyms: | SERTAD1, SEI1, TRIP-Br1 |
| Background: |
| UniProt Protein Function: | SERTAD1: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a). |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Transcription regulation Chromosomal Location of Human Ortholog: 19q13.1-q13.2 Molecular Function:protein binding Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; regulation of cyclin-dependent protein kinase activity |
| UniProt Code: | Q9UHV2 |
| NCBI GenInfo Identifier: | 153792060 |
| NCBI Gene ID: | 29950 |
| NCBI Accession: | NP_037508.2 |
| UniProt Secondary Accession: | Q9UHV2,Q9BUE7, |
| UniProt Related Accession: | Q9UHV2 |
| Molecular Weight: | 24,704 Da |
| NCBI Full Name: | SERTA domain-containing protein 1 |
| NCBI Synonym Full Names: | SERTA domain containing 1 |
| NCBI Official Symbol: | SERTAD1 |
| NCBI Official Synonym Symbols: | SEI1; TRIP-Br1 |
| NCBI Protein Information: | SERTA domain-containing protein 1; CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; SEI-1; transcriptional regulator interacting with the PHD-bromodomain 1 |
| UniProt Protein Name: | SERTA domain-containing protein 1 |
| UniProt Synonym Protein Names: | CDK4-binding protein p34SEI1; SEI-1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP-Br1 |
| UniProt Gene Name: | SERTAD1 |
| UniProt Entry Name: | SRTD1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SERTAD1 antibody (CAB8621) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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