Cell Biology Antibodies 13
Anti-SERPINB7 Antibody (CAB17574)
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- SKU:
- CAB17574
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SERPINB7 Antibody |
| Antibody SKU: | CAB17574 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of Human SERPINB7. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | A synthetic peptide of Human SERPINB7. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8710 |
| Uniprot: | O75635 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | MEGSIN, PPKN, TP55, SERPINB7 |
| Background: | This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Protein Function: | SERPINB7: Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin. Belongs to the serpin family. Ov-serpin subfamily. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.33 Cellular Component: extracellular space; cytoplasm Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: positive regulation of transforming growth factor-beta1 production; positive regulation of collagen biosynthetic process Disease: Palmoplantar Keratoderma, Nagashima Type |
| NCBI Summary: | This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Code: | O75635 |
| NCBI GenInfo Identifier: | 4505149 |
| NCBI Gene ID: | 8710 |
| NCBI Accession: | NP_003775.1 |
| UniProt Secondary Accession: | O75635,Q1ED45, Q3KPG4, B4DUW8, F5GZC0, |
| UniProt Related Accession: | O75635 |
| Molecular Weight: | 41,174 Da |
| NCBI Full Name: | serpin B7 isoform 1 |
| NCBI Synonym Full Names: | serpin family B member 7 |
| NCBI Official Symbol: | SERPINB7 |
| NCBI Official Synonym Symbols: | PPKN; TP55; MEGSIN |
| NCBI Protein Information: | serpin B7 |
| UniProt Protein Name: | Serpin B7 |
| UniProt Synonym Protein Names: | Megsin; TP55 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB7 |
| UniProt Entry Name: | SPB7_HUMAN |
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