Cell Biology Antibodies 9
Anti-SERPINB3 Antibody (CAB5418)
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- SKU:
- CAB5418
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SERPINB3 Antibody |
| Antibody SKU: | CAB5418 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SERPINB3 (NP_008850.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SERPINB3 (NP_008850.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNSL SEAN TKFM FDLF QQFR KSKE NNIF YSPI SITS ALGM VLLG AKDN TAQQ IKKV LHFD QVTE NTTG KAAT YHVD RSGN VHHQ FQKL LTEF NKST DAYE LKIA NKLF GEKT YLFL QEYL DAIK KFYQ TSVE SVDF ANAP EESR KKIN SWVE SQTN EKIK NLIP EGNI GSNT TLVL VNAI YFKG QWEK KFNK EDTK EEKF WPNK NTYK SIQM MRQY TSFH FASL EDVQ AK |
| Gene ID: | 6317 |
| Uniprot: | P29508 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 38kDa/44kDa |
| Observed MW: | 45kDa |
| Synonyms: | SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, SSCA1, T4-A, serpin B3 |
| Background: |
| UniProt Protein Function: | SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle Molecular Function:cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity Biological Process: negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation |
| UniProt Code: | P29508 |
| NCBI GenInfo Identifier: | 20141712 |
| NCBI Gene ID: | 6317 |
| NCBI Accession: | P29508.2 |
| UniProt Secondary Accession: | P29508,Q53H28, Q53YB5, Q86VF3, Q86W04, Q8IWL4, Q8IXI3 Q96J21, Q9BYF8, A6NDM2, B2RBT5, B3W5Y6, |
| UniProt Related Accession: | P29508 |
| Molecular Weight: | 38,550 Da |
| NCBI Full Name: | Serpin B3 |
| NCBI Synonym Full Names: | serpin family B member 3 |
| NCBI Official Symbol: | SERPINB3 |
| NCBI Official Synonym Symbols: | SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD |
| NCBI Protein Information: | serpin B3 |
| UniProt Protein Name: | Serpin B3 |
| UniProt Synonym Protein Names: | Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB3 |
| UniProt Entry Name: | SPB3_HUMAN |
 | Western blot analysis of extracts of mouse eye, using SERPINB3 antibody (CAB5418) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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