Anti-SerpinB3 Antibody (CAB0455)
- SKU:
- CAB0455
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SERPINB3
- Synonyms:
- HsT1196
- Synonyms:
- SCC
- Synonyms:
- SCCA-1
- Synonyms:
- SCCA-PD
- Synonyms:
- SCCA1
- Synonyms:
- SSCA1
- Synonyms:
- T4-A
- Synonyms:
- serpin B3
- Research Area:
- Cell Biology
Description
| Product Name: | SerpinB3 Rabbit mAb |
| Product Code: | CAB0455 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, SSCA1, T4-A, serpin B3 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SerpinB3. |
| Applications: | IHC |
| Recommended Dilutions: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthesized peptide derived from human SerpinB3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6317 |
| Uniprot: | P29508 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 39kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle Molecular Function:cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity Biological Process: negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation |
| UniProt Code: | P29508 |
| NCBI GenInfo Identifier: | 20141712 |
| NCBI Gene ID: | 6317 |
| NCBI Accession: | P29508.2 |
| UniProt Secondary Accession: | P29508,Q53H28, Q53YB5, Q86VF3, Q86W04, Q8IWL4, Q8IXI3 Q96J21, Q9BYF8, A6NDM2, B2RBT5, B3W5Y6, |
| UniProt Related Accession: | P29508 |
| Molecular Weight: | 38,550 Da |
| NCBI Full Name: | Serpin B3 |
| NCBI Synonym Full Names: | serpin family B member 3 |
| NCBI Official Symbol: | SERPINB3 |
| NCBI Official Synonym Symbols: | SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD |
| NCBI Protein Information: | serpin B3 |
| UniProt Protein Name: | Serpin B3 |
| UniProt Synonym Protein Names: | Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB3 |
| UniProt Entry Name: | SPB3_HUMAN |
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