Signal Transduction Antibodies 1
Anti-SERPINA6 Antibody (CAB13609)
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- SKU:
- CAB13609
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SERPINA6 Antibody |
| Antibody SKU: | CAB13609 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, HepG2, HL-60, HT-29, NCI-H460, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SLEL LESF SADI KHYY ESEV LAMN FQDW ATAS RQIN SYVK NKTQ GKIV DLFS GLDS PAIL VLVN YIFF KGTW TQPF DLAS TREE NFYV DETT VVKV PMML QSST ISYL HDAE LPCQ LVQM NYVG NGTV FFIL PDKG KMNT VIAA LSRD TINR WSAG LTSS QVDL YIPK VTIS GVYD LGDV LEEM GIAD LFTN QANF SRIT QDAQ LKSS KVVH KAVL QLNE EGVD TAGS TGVT LNLT SKPI ILRF NQPF IIMI FDHF TWSS LFLA RVMN PV |
| Gene ID: | 866 |
| Uniprot: | P08185 |
| Cellular Location: | Secreted |
| Calculated MW: | 45kDa |
| Observed MW: | 43kDa |
| Synonyms: | SERPINA6, CBG |
| Background: | This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. |
| UniProt Code: | P08185 |
| NCBI GenInfo Identifier: | 115851 |
| NCBI Gene ID: | 866 |
| NCBI Accession: | P08185.1 |
| UniProt Secondary Accession: | P08185,Q7Z2Q9, A8K456, |
| UniProt Related Accession: | P08185 |
| Molecular Weight: | 45,141 Da |
| NCBI Full Name: | Corticosteroid-binding globulin |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| NCBI Official Symbol: | SERPINA6 |
| NCBI Official Synonym Symbols: | CBG |
| NCBI Protein Information: | corticosteroid-binding globulin; serpin A6; transcortin; corticosteroid binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| UniProt Protein Name: | Corticosteroid-binding globulin |
| UniProt Synonym Protein Names: | Serpin A6; Transcortin |
| UniProt Gene Name: | SERPINA6 |
| UniProt Entry Name: | CBG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SERPINA6 antibody (CAB13609) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). |
 | Immunohistochemistry of paraffin-embedded rat intestine using SERPINA6 Antibody (CAB13609) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon using SERPINA6 Antibody (CAB13609) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using SERPINA6 Antibody (CAB13609) at dilution of 1:100 (40x lens). |
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