Cell Biology Antibodies 4

Anti-SERPINA12 Antibody (CAB14160)

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SKU:
CAB14160
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SERPINA12 Antibody
Antibody SKU:CAB14160
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LLKP SFSP RNYK ALSE VQGW KQRM AAKE LARQ NMDL GFKL LKKL AFYN PGRN IFLS PLSI STAF SMLC LGAQ DSTL DEIK QGFN FRKM PEKD LHEG FHYI IHEL TQKT QDLK LSIG NTLF IDQR LQPQ RKFL EDAK NFYS AETI LTNF QNLE MAQK QIND FISQ KTHG KINN LIEN IDPG TVML LANY IFFR ARWK HEFD PNVT KEED FFLE KNSS VKVP MMFR SGIY QVGY DDKL SCTI LEIP YQKN ITAI FILP DEGK LKHL EKGL QVDT FSRW KTLL SRRV VDVS VPRL HMTG TFDL K
Gene ID:145264
Uniprot:Q8IW75
Cellular Location:Secreted
Calculated MW:47kDa
Observed MW:Refer to figures
Synonyms:SERPINA12, OL-64
Background:
UniProt Protein Function:SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family.
UniProt Protein Details:

Protein type:Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q32.13

Cellular Component: extracellular space; plasma membrane

Molecular Function:serine-type endopeptidase inhibitor activity

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; negative regulation of lipid biosynthetic process; negative regulation of gluconeogenesis; positive regulation of insulin receptor signaling pathway

UniProt Code:Q8IW75
NCBI GenInfo Identifier:74728144
NCBI Gene ID:145264
NCBI Accession:Q8IW75.1
UniProt Related Accession:Q8IW75
Molecular Weight:47,175 Da
NCBI Full Name:Serpin A12
NCBI Synonym Full Names:serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
NCBI Official Symbol:SERPINA12  
NCBI Official Synonym Symbols:OL-64  
NCBI Protein Information:serpin A12; vaspin; visceral adipose-specific SERPIN; visceral adipose tissue-derived serine protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
UniProt Protein Name:Serpin A12
UniProt Synonym Protein Names:OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin
Protein Family:Serpin
UniProt Gene Name:SERPINA12  
UniProt Entry Name:SPA12_HUMAN
Anti-SERPINA12 Antibody (CAB14160)Immunofluorescence analysis of PC-12 cells using SERPINA12 antibody (CAB14160) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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