Cardiovascular Antibodies

Anti-SERPINA10 Antibody (CAB4717)

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SKU:
CAB4717
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
SERPINA10
Synonyms:
PZI
Synonyms:
ZPI
Research Area:
Cardiovascular

Description

Product Name:SERPINA10 Rabbit pAb
Product Code:CAB4717
Size:20uL, 50uL, 100uL
Synonyms:SERPINA10, PZI, ZPI
Applications:WB, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1).
Applications:WB, IF
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:20 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FAFI HKDF DVKE TFFN LSKR YFDT ECVP MNFR NASQ AKRL MNHY INKE TRGK IPKL FDEI NPET KLIL VDYI LFKG KWLT PFDP VFTE VDTF HLDK YKTI KVPM MYGA GKFA STFD KNFR CHVL KLPY QGNA TMLV VLME KMGD HLAL EDYL TTDL VETW LRNM KTRN MEVF FPKF KLDQ KYEM HELL RQMG IRRI FSPF ADLS ELSA TGRN LQVS RVLQ RTVI EVDE RGTE AVAG ILSE ITAY SMPP VIKV DRPF HFMI YEET SGML LFLG RVVN PTLL
Gene ID:51156
Uniprot:Q9UK55
Cellular Location:Secreted
Calculated MW:50kDa
Observed MW:51kDa
UniProt Protein Function:SERPINA10: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Belongs to the serpin family.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q32.13

Cellular Component: extracellular space

Molecular Function:serine-type endopeptidase inhibitor activity; heparin binding

Biological Process: regulation of acrosome reaction; blood coagulation

NCBI Summary:The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]
UniProt Code:Q9UK55
NCBI GenInfo Identifier:12585541
NCBI Gene ID:51156
NCBI Accession:Q9UK55.1
UniProt Secondary Accession:Q9UK55,Q6UWX9, Q86U20, A5Z2A5,
UniProt Related Accession:Q9UK55
Molecular Weight:444
NCBI Full Name:Protein Z-dependent protease inhibitor
NCBI Synonym Full Names:serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
NCBI Official Symbol:SERPINA10  
NCBI Official Synonym Symbols:PZI; ZPI  
NCBI Protein Information:protein Z-dependent protease inhibitor; serpin A10; PZ-dependent protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
UniProt Protein Name:Protein Z-dependent protease inhibitor
UniProt Synonym Protein Names:Serpin A10
Protein Family:Protein Z-dependent protease inhibitor
UniProt Gene Name:SERPINA10  
UniProt Entry Name:ZPI_HUMAN
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Cardiovascular Recombinant Proteins

system_update_altDatasheetHuman SerpinA10/SERPINA10 Recombinant Protein Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted