Cell Biology Antibodies 11
Anti-Serpin A12 Antibody (CAB8074)
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- SKU:
- CAB8074
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | SERPINA12 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8074 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LLKP SFSP RNYK ALSE VQGW KQRM AAKE LARQ NMDL GFKL LKKL AFYN PGRN IFLS PLSI STAF SMLC LGAQ DSTL DEIK QGFN FRKM PEKD LHEG FHYI IHEL TQKT QDLK LSIG NTLF IDQR LQPQ RKFL EDAK NFYS AETI LTNF QNLE MAQK QIND FISQ KTHG KINN LIEN IDPG TVML LANY IFFR ARWK HEFD PNVT KEED FFLE KNSS VKVP MMFR SGIY QVGY DDKL SCTI LEIP YQKN ITAI FILP DEGK LKHL EKGL QVDT FSRW KTLL SRRV VDVS VPRL HMTG TFDL K |
| Gene ID: | 145264 |
| Uniprot: | Q8IW75 |
| Cellular Location: | Secreted |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
| Synonyms: | SERPINA12, OL-64 |
| Background: |
| UniProt Protein Function: | SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family. |
| UniProt Protein Details: | Protein type:Inhibitor; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 14q32.13 Cellular Component: extracellular space; plasma membrane Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: positive regulation of phosphoinositide 3-kinase cascade; negative regulation of lipid biosynthetic process; negative regulation of gluconeogenesis; positive regulation of insulin receptor signaling pathway |
| UniProt Code: | Q8IW75 |
| NCBI GenInfo Identifier: | 74728144 |
| NCBI Gene ID: | 145264 |
| NCBI Accession: | Q8IW75.1 |
| UniProt Related Accession: | Q8IW75 |
| Molecular Weight: | 47,175 Da |
| NCBI Full Name: | Serpin A12 |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
| NCBI Official Symbol: | SERPINA12 |
| NCBI Official Synonym Symbols: | OL-64 |
| NCBI Protein Information: | serpin A12; vaspin; visceral adipose-specific SERPIN; visceral adipose tissue-derived serine protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
| UniProt Protein Name: | Serpin A12 |
| UniProt Synonym Protein Names: | OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINA12 |
| UniProt Entry Name: | SPA12_HUMAN |
 | Western blot analysis of extracts of mouse brain, using SERPINA12 Antibody (CAB8074) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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