Cell Biology Antibodies 13
Anti-SEPT1 Antibody (CAB17471)
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- SKU:
- CAB17471
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SEPT1 Antibody |
| Antibody SKU: | CAB17471 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human SEPT1 (NP_443070.5). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | K562, mouse liver, mouse ovary, rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human SEPT1 (NP_443070.5). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IPFA VVGS CEVV RDGG NRPV RGRR YSWG TVEV ENPH HCDF LNLR RMLV QTHL QDLK EVTH DLLY EGYR ARCL QSLA RPGA RDRA SRSK LSRQ SATE IPLP M |
| Gene ID: | 1731 |
| Uniprot: | Q8WYJ6 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 42kDa |
 | Western blot - SEPT1 Polyclonal Antibody (CAB17471) |
| Synonyms: | DIFF6, LARP, PNUTL3, SEP1, SEPT1 |
| Background: | This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
| UniProt Protein Function: | SEPT1: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the septin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Hydrolase; Cytoskeletal Chromosomal Location of Human Ortholog: 16p11.1 Molecular Function:protein binding |
| NCBI Summary: | This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q8WYJ6 |
| NCBI GenInfo Identifier: | 20178107 |
| NCBI Gene ID: | 1731 |
| NCBI Accession: | Q8WYJ6.2 |
| UniProt Secondary Accession: | Q8WYJ6,Q658T1, Q8NEZ1, Q96EL4, Q9H285, B4DVE6, |
| UniProt Related Accession: | Q8WYJ6 |
| Molecular Weight: | 18,354 Da |
| NCBI Full Name: | Septin-1 |
| NCBI Synonym Full Names: | septin 1 |
| NCBI Official Symbol: | SEPT1 |
| NCBI Official Synonym Symbols: | LARP; SEP1; DIFF6; PNUTL3 |
| NCBI Protein Information: | septin-1 |
| UniProt Protein Name: | Septin-1 |
| UniProt Synonym Protein Names: | LARP; Peanut-like protein 3; Serologically defined breast cancer antigen NY-BR-24 |
| UniProt Gene Name: | SEPT1 |
| UniProt Entry Name: | SEPT1_HUMAN |
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