Anti-SEPHS1 Antibody (CAB19920)

Name: Anti-SEPHS1 Antibody (CAB19920)[KO Validated]
Brand: KO Validated Antibodies 2
SKU: CAB19920
Availability: OutOfStock

Antibody Name:	Anti-SEPHS1 Antibody [KO Validated]
Antibody SKU:	CAB19920
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant protein of human SEPHS1.

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	293T

Immunogen:	Recombinant protein of human SEPHS1.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	22929
Uniprot:	P49903
Cellular Location:	Cell membrane, Cytoplasm, Nucleus membrane
Calculated MW:	35kDa/42kDa
Observed MW:	41KDa

Anti-SEPHS1 Antibody [KO Validated] (CAB19920)

Western blot analysis of extracts from normal (control) and SEPHS1 knockout (KO) 293T cells, using SEPHS1 antibody (CAB19920) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

Synonyms:	SEPHS1, SELD, SPS, SPS1, selenide
Background:	This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.

UniProt Protein Function:	SEPHS1: Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class II subfamily.
UniProt Protein Details:	Protein type:Other Amino Acids Metabolism - selenoamino acid; Kinase, other; EC 2.7.9.3 Chromosomal Location of Human Ortholog: 10p14 Cellular Component: nuclear membrane; cytoplasm; plasma membrane Molecular Function:protein binding; protein homodimerization activity; GTP binding; selenide, water dikinase activity; protein heterodimerization activity; ATP binding Biological Process: protein modification process; phosphorylation
NCBI Summary:	This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010]
UniProt Code:	P49903
NCBI GenInfo Identifier:	27151792
NCBI Gene ID:	22929
NCBI Accession:	P49903.2
UniProt Secondary Accession:	P49903,Q5T5U8, Q5T5U9, Q9BVT4, B4DWK0, D3DRS9, D6PSQ9
UniProt Related Accession:	P49903
Molecular Weight:	392
NCBI Full Name:	Selenide, water dikinase 1
NCBI Synonym Full Names:	selenophosphate synthetase 1
NCBI Official Symbol:	SEPHS1
NCBI Official Synonym Symbols:	SPS; SELD; SPS1
NCBI Protein Information:	selenide, water dikinase 1; selenium donor protein 1; selenophosphate synthase 1; selenophosphate synthetase 1 +E9; selenophosphate synthetase 1 +E9a; selenophosphate synthetase 1 major; selenophosphate synthetase 1 delta E2; selenophosphate synthetase 1 delta E8
UniProt Protein Name:	Selenide, water dikinase 1
UniProt Synonym Protein Names:	Selenium donor protein 1; Selenophosphate synthase 1
UniProt Gene Name:	SEPHS1
UniProt Entry Name:	SPS1_HUMAN