Cell Biology Antibodies 14
Anti-SENP2 Antibody (CAB17994)
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- SKU:
- CAB17994
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SENP2 Antibody |
| Antibody SKU: | CAB17994 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SENP2. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | rat lung, rat testis |
| Immunogen: | Recombinant protein of human SENP2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 59343 |
| Uniprot: | Q9HC62 |
| Cellular Location: | |
| Calculated MW: | 68kDa |
| Observed MW: | 68kDa |
 | Western blot - SENP2 Polyclonal Antibody (CAB17994) |
| Synonyms: | AXAM2, SMT3IP2, SENP2 |
| Background: |
| UniProt Protein Function: | SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Belongs to the peptidase C48 family. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.22.68 Chromosomal Location of Human Ortholog: 3q27.2 Cellular Component: nuclear pore; nucleoplasm; PML body Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: fat cell differentiation; negative regulation of protein ubiquitination; positive regulation of protein ubiquitination; protein destabilization; protein desumoylation; protein sumoylation |
| NCBI Summary: | SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9HC62 |
| NCBI GenInfo Identifier: | 143811458 |
| NCBI Gene ID: | 59343 |
| NCBI Accession: | Q9HC62.3 |
| UniProt Secondary Accession: | Q9HC62,Q8IW97, Q96SR2, Q9P2L5, B4DQ42, |
| UniProt Related Accession: | Q9HC62 |
| Molecular Weight: | 66,358 Da |
| NCBI Full Name: | Sentrin-specific protease 2 |
| NCBI Synonym Full Names: | SUMO1/sentrin/SMT3 specific peptidase 2 |
| NCBI Official Symbol: | SENP2 |
| NCBI Official Synonym Symbols: | AXAM2; SMT3IP2 |
| NCBI Protein Information: | sentrin-specific protease 2 |
| UniProt Protein Name: | Sentrin-specific protease 2 |
| UniProt Synonym Protein Names: | Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2 |
| Protein Family: | Sentrin-specific protease |
| UniProt Gene Name: | SENP2 |
| UniProt Entry Name: | SENP2_HUMAN |
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