Cell Biology Antibodies 18
Anti-SEMA3E Antibody (CAB18409)
- SKU:
- CAB18409
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SEMA3E Antibody |
| Antibody SKU: | CAB18409 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SEMA3E. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human SEMA3E. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9723 |
| Uniprot: | O15041 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | M-SEMAH, M-SemaK, SEMAH, coll-5, SEMA3E |
| Background: |
| UniProt Protein Function: | SEMA3E: a secreted protein of the semaphorin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 7q21.11 Cellular Component: extracellular space; membrane; extracellular region Molecular Function:protein binding; receptor activity; semaphorin receptor binding Biological Process: patterning of blood vessels; axon guidance; regulation of cell shape; negative regulation of angiogenesis; synapse organization and biogenesis; sprouting angiogenesis; negative regulation of cell-matrix adhesion Disease: Charge Syndrome |
| NCBI Summary: | Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] |
| UniProt Code: | O15041 |
| NCBI GenInfo Identifier: | 8134690 |
| NCBI Gene ID: | 9723 |
| NCBI Accession: | O15041.1 |
| UniProt Secondary Accession: | O15041,Q75M94, Q75M97, B4E1P1, |
| UniProt Related Accession: | O15041 |
| Molecular Weight: | 82,424 Da |
| NCBI Full Name: | Semaphorin-3E |
| NCBI Synonym Full Names: | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| NCBI Official Symbol: | SEMA3E |
| NCBI Official Synonym Symbols: | SEMAH; coll-5; M-SEMAH; M-SemaK |
| NCBI Protein Information: | semaphorin-3E |
| UniProt Protein Name: | Semaphorin-3E |
| Protein Family: | Semaphorin |
| UniProt Gene Name: | SEMA3E |
| UniProt Entry Name: | SEM3E_HUMAN |