Cell Biology Antibodies 6

Anti-SEC22B Antibody (CAB15358)

(No reviews yet) Write a Review
SKU:
CAB15358
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SEC22B Antibody
Antibody SKU:CAB15358
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 85-195 of human SEC22B (NP_004883.3).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse
Positive Samples:A-431, LO2, HeLa, Mouse thymus, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 85-195 of human SEC22B (NP_004883.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FAYL EDLH SEFD EQHG KKVP TVSR PYSF IEFD TFIQ KTKK LYID SRAR RNLG SINT ELQD VQRI MVAN IEEV LQRG EALS ALDS KANN LSSL SKKY RQDA KYLN MRST YAK
Gene ID:9554
Uniprot:O75396
Cellular Location:Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus, Melanosome, Single-pass type IV membrane protein, cis-Golgi network membrane, trans-Golgi network membrane
Calculated MW:24kDa
Observed MW:25kDa
Synonyms:SEC22B, ERS-24, SEC22L1
Background:The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.
UniProt Protein Function:SEC22B: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. Belongs to the synaptobrevin family.
UniProt Protein Details:

Protein type:Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; integral to membrane; ER-Golgi intermediate compartment; melanosome

Molecular Function:protein binding; syntaxin binding

Biological Process: ER to Golgi vesicle-mediated transport; protein transport; positive regulation of protein catabolic process; regulation of organelle organization and biogenesis

NCBI Summary:The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.[provided by RefSeq, Sep 2009]
UniProt Code:O75396
NCBI GenInfo Identifier:317373544
NCBI Gene ID:9554
NCBI Accession:O75396.4
UniProt Related Accession:O75396
Molecular Weight:
NCBI Full Name:Vesicle-trafficking protein SEC22b
NCBI Synonym Full Names:SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
NCBI Official Symbol:SEC22B  
NCBI Official Synonym Symbols:ERS-24; SEC22L1  
NCBI Protein Information:vesicle-trafficking protein SEC22b
UniProt Protein Name:Vesicle-trafficking protein SEC22b
UniProt Synonym Protein Names:ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1
Protein Family:Vesicle-trafficking protein
UniProt Gene Name:SEC22B  
UniProt Entry Name:SC22B_HUMAN
Anti-SEC22B Antibody (CAB15358)Western blot analysis of extracts of various cell lines, using SEC22B antibody (CAB15358) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products