Cell Biology Antibodies 5

Anti-SEC16B Antibody (CAB14678)

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SKU:
CAB14678
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SEC16B Antibody
Antibody SKU:CAB14678
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human SEC16B (NP_149118.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, Mouse pancreas
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human SEC16B (NP_149118.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DPPA SAAW SPVQ ADVS SAGP KAPM KFYI PHVP VSFG PGGQ LVHV GPSS PTDG QAAL VELH SMEV ILND SEEQ EEMR SFSG PLIR EDVH KVDI MTFC QQKA AQSC KSET LGSR DSAL LWQL LVLL CRQN GSMV GSDI AELL MQDC KKLE KYKR QPPV ANLI NLTD EDWP VLSS GTPN LLTG EIPP SVET PAQI VEKF TRLL YYGR KKEA LEWA MKNH LWGH ALFL SSKM DPQT YSWV MSGF TSTL ALND PLQT LFQL MSGR IPQA ATCC GEKQ WGDW RPHL AVIL SNQA GDPE LYQR AIVA I
Gene ID:89866
Uniprot:Q96JE7
Cellular Location:Endoplasmic reticulum membrane, Golgi apparatus membrane, Peripheral membrane protein
Calculated MW:59kDa/70kDa/116kDa
Observed MW:117kDa
Synonyms:SEC16B, LZTR2, PGPR-p117, RGPR, SEC16S
Background:
UniProt Protein Function:SEC16B: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization. Belongs to the SEC16 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle

Biological Process: COPII coating of Golgi vesicle; peroxisome fission; endoplasmic reticulum organization and biogenesis; protein transport; peroxisome organization and biogenesis

NCBI Summary:SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009]
UniProt Code:Q96JE7
NCBI GenInfo Identifier:116235480
NCBI Gene ID:89866
NCBI Accession:NP_149118
UniProt Secondary Accession:Q96JE7,Q5HYF6, Q8N7D6, Q96GX6, A3EYF1,
UniProt Related Accession:Q96JE7
Molecular Weight:59,124 Da
NCBI Full Name:protein transport protein Sec16B
NCBI Synonym Full Names:SEC16 homolog B, endoplasmic reticulum export factor
NCBI Official Symbol:SEC16B  
NCBI Official Synonym Symbols:RGPR; LZTR2; SEC16S; PGPR-p117  
NCBI Protein Information:protein transport protein Sec16B
UniProt Protein Name:Protein transport protein Sec16B
UniProt Synonym Protein Names:Leucine zipper transcription regulator 2; Regucalcin gene promoter region-related protein p117; RGPR-p117; SEC16 homolog B
UniProt Gene Name:SEC16B  
UniProt Entry Name:SC16B_HUMAN
Anti-SEC16B Antibody (CAB14678)Western blot analysis of extracts of various cell lines, using SEC16B antibody (CAB14678) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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