Metabolism Antibodies 1

Anti-SDS Antibody (CAB12898)

(No reviews yet) Write a Review
SKU:
CAB12898
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SDS Antibody
Antibody SKU:CAB12898
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 90-170 of human SDS (NP_006834.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 90-170 of human SDS (NP_006834.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TTPA LTIE RLKN EGAT VKVV GELL DEAF ELAK ALAK NNPG WVYI PPFD DPLI WEGH ASIV KELK ETLW EKPG AIAL SVGG G
Gene ID:10993
Uniprot:P20132
Cellular Location:Cytoplasm
Calculated MW:34kDa
Observed MW:35kDa
Synonyms:SDS, SDH
Background:This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
UniProt Protein Function:SDS: one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine; EC 4.3.1.17; EC 4.3.1.19; Lyase

Chromosomal Location of Human Ortholog: 12q24.13

Cellular Component: cytosol; mitochondrion

Molecular Function:L-serine ammonia-lyase activity; protein homodimerization activity; pyridoxal phosphate binding

Biological Process: L-serine catabolic process; pyruvate biosynthetic process

NCBI Summary:This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]
UniProt Code:P20132
NCBI GenInfo Identifier:229462819
NCBI Gene ID:10993
NCBI Accession:P20132.2
UniProt Secondary Accession:P20132,A8K9P5,
UniProt Related Accession:P20132
Molecular Weight:35kDa
NCBI Full Name:L-serine dehydratase/L-threonine deaminase
NCBI Synonym Full Names:serine dehydratase
NCBI Official Symbol:SDS  
NCBI Official Synonym Symbols:SDH  
NCBI Protein Information:L-serine dehydratase/L-threonine deaminase
UniProt Protein Name:L-serine dehydratase/L-threonine deaminase
UniProt Synonym Protein Names:L-serine deaminase; L-threonine dehydratase (EC:4.3.1.19); TDH
Protein Family:SDS degradation transcriptional activation protein
UniProt Gene Name:SDS  
Anti-SDS Antibody (CAB12898)Western blot analysis of extracts of various cell lines, using SDS antibody (CAB12898) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products