Cell Biology Antibodies 8
Anti-SCTR Antibody (CAB3125)
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- SKU:
- CAB3125
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SCTR Antibody |
| Antibody SKU: | CAB3125 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SCTR |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant protein of human SCTR |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6344 |
| Uniprot: | P47872 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 50kDa |
| Observed MW: | 50kDa |
| Synonyms: | SCTR, SR |
| Background: | The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. |
| UniProt Protein Function: | SCTR: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 2; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 2q14.1 Cellular Component: integral to plasma membrane; cytoplasmic microtubule; plasma membrane Molecular Function:secretin receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; digestion; excretion |
| NCBI Summary: | The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47872 |
| NCBI GenInfo Identifier: | 2506489 |
| NCBI Gene ID: | 6344 |
| NCBI Accession: | P47872.2 |
| UniProt Secondary Accession: | P47872,Q12961, Q13213, Q53T00, |
| UniProt Related Accession: | P47872 |
| Molecular Weight: | 50kDa |
| NCBI Full Name: | Secretin receptor |
| NCBI Synonym Full Names: | secretin receptor |
| NCBI Official Symbol: | SCTR |
| NCBI Official Synonym Symbols: | SR |
| NCBI Protein Information: | secretin receptor; pancreatic secretin receptor |
| UniProt Protein Name: | Secretin receptor |
| Protein Family: | Secretin receptor |
| UniProt Gene Name: | SCTR |
| UniProt Entry Name: | SCTR_HUMAN |
 | Western blot analysis of extracts of mouse liver, using SCTR antibody (CAB3125). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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