Cell Biology Antibodies 14
Anti-SCT Antibody (CAB17944)
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- SKU:
- CAB17944
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SCT Antibody |
| Antibody SKU: | CAB17944 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-121 of human SCT (NP_068739.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-121 of human SCT (NP_068739.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RPAP PRAR RHSD GTFT SELS RLRE GARL QRLL QGLV GKRS EQDA ENSM AWTR LSAG LLCP SGSN MPIL QAWM PLDG TWSP WLPP GPMV SEPA GAAA EGTL RPR |
| Gene ID: | 6343 |
| Uniprot: | P09683 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | SCT |
| Background: |
| UniProt Protein Function: | SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: extracellular region Molecular Function:hormone activity Biological Process: dentate gyrus development; visual learning; negative regulation of neuron apoptosis; pancreatic juice secretion |
| NCBI Summary: | Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09683 |
| NCBI GenInfo Identifier: | 12231018 |
| NCBI Gene ID: | 6343 |
| NCBI Accession: | P09683.2 |
| UniProt Related Accession: | P09683 |
| Molecular Weight: | 13,016 Da |
| NCBI Full Name: | Secretin |
| NCBI Synonym Full Names: | secretin |
| NCBI Official Symbol: | SCT |
| NCBI Protein Information: | secretin; prepro-secretin |
| UniProt Protein Name: | Secretin |
| Protein Family: | Secretin |
| UniProt Gene Name: | SCT |
| UniProt Entry Name: | SECR_HUMAN |
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