Signal Transduction Antibodies 3
Anti-SCN2B Antibody (CAB7723)
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- SKU:
- CAB7723
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SCN2B Antibody |
| Antibody SKU: | CAB7723 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-160 of human SCN2B (NP_004579.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | SW620, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-160 of human SCN2B (NP_004579.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEVT VPAT LNVL NGSD ARLP CTFN SCYT VNHK QFSL NWTY QECN NCSE EMFL QFRM KIIN LKLE RFQD RVEF SGNP SKYD VSVM LRNV QPED EGIY NCYI MNPP DRHR GHGK IHLQ VLME EPPE RDST VAV |
| Gene ID: | 6327 |
| Uniprot: | O60939 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
| Synonyms: | SCN2B, ATFB14 |
| Background: | The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. |
| NCBI Summary: | The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015] |
| UniProt Code: | O60939 |
| NCBI GenInfo Identifier: | 22477313 |
| NCBI Gene ID: | 6327 |
| NCBI Accession: | BC036793 |
| UniProt Secondary Accession: | O60939,O75302, Q9UNN3, |
| UniProt Related Accession: | O60939 |
| Molecular Weight: | 24,326 Da |
| NCBI Full Name: | Homo sapiens sodium channel, voltage-gated, type II, beta, mRNA |
| NCBI Synonym Full Names: | sodium voltage-gated channel beta subunit 2 |
| NCBI Official Symbol: | SCN2B |
| NCBI Official Synonym Symbols: | ATFB14 |
| NCBI Protein Information: | sodium channel subunit beta-2 |
| UniProt Protein Name: | |
| Protein Family: | Sodium channel |
| UniProt Gene Name: |
 | Western blot analysis of extracts of various cell lines, using SCN2B antibody (CAB7723) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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