Cell Biology Antibodies 6

Anti-SCLY Antibody (CAB15842)

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SKU:
CAB15842
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SCLY Antibody
Antibody SKU:CAB15842
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 284-453 of human SCLY (NP_057594.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 284-453 of human SCLY (NP_057594.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FTPL YPML FGGG QERN FRPG TENT PMIA GLGK AAEL VTQN CEAY EAHM RDVR DYLE ERLE AEFG QKRI HLNS QFPG TQRL PNTC NFSI RGPR LQGH VVLA QCRV LMAS VGAA CHSD HGDQ PSPV LLSY GVPF DVAR NALR LSVG RSTT RAEV DLVV QDLK QAVA QLED QA
Gene ID:51540
Uniprot:Q96I15
Cellular Location:Cytoplasm, cytosol
Calculated MW:33kDa/48kDa
Observed MW:48kDa
Synonyms:SCLY, SCL, hSCL
Background:Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).
UniProt Protein Function:SCLY: Catalyzes the decomposition of L-selenocysteine to L- alanine and elemental selenium. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Lyase; EC 4.4.1.16; Other Amino Acids Metabolism - selenoamino acid

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytosol

Molecular Function:transferase activity; selenocysteine lyase activity; pyridoxal phosphate binding

Biological Process: amino acid metabolic process

NCBI Summary:Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008]
UniProt Code:Q96I15
NCBI GenInfo Identifier:527504087
NCBI Gene ID:51540
NCBI Accession:Q96I15.4
UniProt Secondary Accession:Q96I15,Q53SN1, Q53SN8, Q7L670, Q9NVT7, Q9NZR7, B9A068 J3KN06,
UniProt Related Accession:Q96I15
Molecular Weight:33,957 Da
NCBI Full Name:Selenocysteine lyase
NCBI Synonym Full Names:selenocysteine lyase
NCBI Official Symbol:SCLY  
NCBI Official Synonym Symbols:SCL; hSCL  
NCBI Protein Information:selenocysteine lyase
UniProt Protein Name:Selenocysteine lyase
Protein Family:Selenocysteine lyase
UniProt Gene Name:SCLY  
UniProt Entry Name:SCLY_HUMAN
Anti-SCLY Antibody (CAB15842)Western blot analysis of extracts of various cell lines, using SCLY antibody (CAB15842) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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system_update_altDatasheetHuman SCLY Recombinant Protein Selenocysteine Lyase belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Selenocysteine Lyase exists as a homodi