Cell Biology Antibodies 14

Anti-SCGB1A1 Antibody (CAB16998)

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SKU:
CAB16998
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SCGB1A1 Antibody
Antibody SKU:CAB16998
Antibody Size:20uL, 50uL, 100uL
Application:IHC IF
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1).
Application:IHC IF
Recommended Dilution:IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EICP SFQR VIET LLMD TPSS YEAA MELF SPDQ DMRE AGAQ LKKL VDTL PQKP RESI IKLM EKIA QSSL CN
Gene ID:7356
Uniprot:P11684
Cellular Location:
Calculated MW:9kDa
Observed MW:Refer to figures
Anti-SCGB1A1 Antibody (CAB16998)Immunohistochemistry - SCGB1A1 Polyclonal Antibody (CAB16998)
Synonyms:SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1
Background:This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
UniProt Protein Function:SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.
UniProt Protein Details:

Protein type:Secreted; Cell cycle regulation; Secreted, signal peptide; Inhibitor

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: extracellular space; rough endoplasmic reticulum; nuclear envelope; secretory granule

Molecular Function:protein binding; phospholipase A2 inhibitor activity

Biological Process: response to drug; negative regulation of interleukin-4 production; response to glucocorticoid stimulus; response to lipopolysaccharide; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; signal transduction; regulation of mRNA stability; response to xenobiotic stimulus; response to silicon dioxide; negative regulation of interleukin-13 production; negative regulation of T cell proliferation; response to ozone; negative regulation of interferon-gamma production; response to cytokine stimulus; negative regulation of catalytic activity; regulation of inflammatory response; negative regulation of interleukin-5 production; embryo implantation

Disease: Asthma, Susceptibility To

NCBI Summary:This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
UniProt Code:P11684
NCBI GenInfo Identifier:112672
NCBI Gene ID:7356
NCBI Accession:P11684.1
UniProt Related Accession:P11684
Molecular Weight:16kDa
NCBI Full Name:Uteroglobin
NCBI Synonym Full Names:secretoglobin family 1A member 1
NCBI Official Symbol:SCGB1A1  
NCBI Official Synonym Symbols:UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP  
NCBI Protein Information:uteroglobin
UniProt Protein Name:Uteroglobin
UniProt Synonym Protein Names:Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1
Protein Family:Uteroglobin
UniProt Gene Name:SCGB1A1  
UniProt Entry Name:UTER_HUMAN
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