Name: Anti-SCGB1A1 Antibody (CAB16997)
Brand: Cell Biology Antibodies 7
SKU: CAB16997
Availability: OutOfStock

Antibody Name:	Anti-SCGB1A1 Antibody
Antibody SKU:	CAB16997
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1).

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EICP SFQR VIET LLMD TPSS YEAA MELF SPDQ DMRE AGAQ LKKL VDTL PQKP RESI IKLM EKIA QSSL CN
Gene ID:	7356
Uniprot:	P11684
Cellular Location:
Calculated MW:	9kDa
Observed MW:	Refer to figures

Synonyms:	SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1
Background:	This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

UniProt Protein Function:	SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.
UniProt Protein Details:	Protein type:Secreted; Cell cycle regulation; Secreted, signal peptide; Inhibitor Chromosomal Location of Human Ortholog: 11q12.3 Cellular Component: extracellular space; rough endoplasmic reticulum; nuclear envelope; secretory granule Molecular Function:protein binding; phospholipase A2 inhibitor activity Biological Process: response to drug; negative regulation of interleukin-4 production; response to glucocorticoid stimulus; response to lipopolysaccharide; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; signal transduction; regulation of mRNA stability; response to xenobiotic stimulus; response to silicon dioxide; negative regulation of interleukin-13 production; negative regulation of T cell proliferation; response to ozone; negative regulation of interferon-gamma production; response to cytokine stimulus; negative regulation of catalytic activity; regulation of inflammatory response; negative regulation of interleukin-5 production; embryo implantation Disease: Asthma, Susceptibility To
NCBI Summary:	This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
UniProt Code:	P11684
NCBI GenInfo Identifier:	112672
NCBI Gene ID:	7356
NCBI Accession:	P11684.1
UniProt Related Accession:	P11684
Molecular Weight:	16kDa
NCBI Full Name:	Uteroglobin
NCBI Synonym Full Names:	secretoglobin family 1A member 1
NCBI Official Symbol:	SCGB1A1
NCBI Official Synonym Symbols:	UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP
NCBI Protein Information:	uteroglobin
UniProt Protein Name:	Uteroglobin
UniProt Synonym Protein Names:	Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1
Protein Family:	Uteroglobin
UniProt Gene Name:	SCGB1A1
UniProt Entry Name:	UTER_HUMAN

	Western blot analysis of extracts of mouse lung, using SCGB1A1 antibody (CAB16997) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded rat lung using SCGB1A1 antibody (CAB16997) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse lung using SCGB1A1 antibody (CAB16997) at dilution of 1:100 (40x lens).
	Immunofluorescence analysis of mouse lung cells using SCGB1A1 antibody (CAB16997) at dilution of 1:100. Blue: DAPI for nuclear staining.