Cell Biology Antibodies 11
Anti-SCG3 Antibody (CAB7799)
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- SKU:
- CAB7799
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SCG3 Antibody |
| Antibody SKU: | CAB7799 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 22Rv1, HepG2, Mouse brain, Mouse lung, Mouse heart, Rat brain, Rat lung, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KLIS KEAN NYEE DPNK PTSW TENQ AGKI PEKV TPMA AIQD GLAK GEND ETVS NTLT LTNG LERR TKTY SEDN FEEL QYFP NFYA LLKS IDSE KEAK EKET LITI MKTL IDFV KMMV KYGT ISPE EGVS YLEN LDEM IALQ TKNK LEKN ATDN ISKL FPAP SEKS HEET DSTK EEAA KMEK EYGS LKDS TKDD NSNP GGKT DEPK GKTE AYLE AIRK NIEW LKKH DKKG NKED YDLS KMRD FINK QADA YVEK GILD KEEA EAIK RIYS SL |
| Gene ID: | 29106 |
| Uniprot: | Q8WXD2 |
| Cellular Location: | Cytoplasmic vesicle, Peripheral membrane protein, Secreted, secretory vesicle lumen, secretory vesicle membrane |
| Calculated MW: | 26kDa/53kDa |
| Observed MW: | 53kDa |
| Synonyms: | SCG3, SGIII |
| Background: | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | SCG3: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 15q21 Cellular Component: cytoplasmic vesicle; extracellular region Biological Process: blood coagulation; platelet activation; platelet degranulation |
| NCBI Summary: | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| UniProt Code: | Q8WXD2 |
| NCBI GenInfo Identifier: | 46397796 |
| NCBI Gene ID: | 29106 |
| NCBI Accession: | Q8WXD2.3 |
| UniProt Secondary Accession: | Q8WXD2,Q96C83, Q96GE8, Q9Y6G7, A8K2B0, B3KQP6, B4DK99 F5H3R8, |
| UniProt Related Accession: | Q8WXD2 |
| Molecular Weight: | 26,909 Da |
| NCBI Full Name: | Secretogranin-3 |
| NCBI Synonym Full Names: | secretogranin III |
| NCBI Official Symbol: | SCG3 |
| NCBI Official Synonym Symbols: | SGIII |
| NCBI Protein Information: | secretogranin-3 |
| UniProt Protein Name: | Secretogranin-3 |
| UniProt Synonym Protein Names: | Secretogranin III; SgIII |
| Protein Family: | Secretogranin |
| UniProt Gene Name: | SCG3 |
| UniProt Entry Name: | SCG3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SCG3 antibody (CAB7799) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded human stomach using SCG3 antibody (CAB7799) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using SCG3 antibody (CAB7799) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using SCG3 antibody (CAB7799) at dilution of 1:100 (40x lens). |
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