Cell Biology Antibodies 12

Anti-SCAND1 Antibody (CAB8310)

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SKU:
CAB8310
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:SCAND1 Rabbit Polyclonal Antibody
Antibody SKU:CAB8310
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human SCAND1 (NP_057642.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, Mouse kidney, Mouse testis, Mouse thymus, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human SCAND1 (NP_057642.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAT EPIL AATG SPAA VPPE KLEG AGSS SAPE RNCV GSSL PEAS PPAP EPSS PNAA VPEA IPTP RAAA SAAL ELPL GPAP VSVA PQAE AEAR STPG PAGS RLGP ETFR QRFR QFRY QDAA GPRE AFRQ LREL SRQW LRPD IRTK EQIV EMLV QEQL LAIL PEAA RARR IRRR TDVR ITG
Gene ID:51282
Uniprot:P57086
Cellular Location:Nucleus
Calculated MW:19kDa
Observed MW:19kDa
Synonyms:SCAND1, RAZ1, SDP1
Background:This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:SCAND1: may regulate transcriptional activity. Contains a SCAN domain, which mediates protein interactions.
UniProt Protein Details:

Protein type:Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 20q11.1-q11.23

Cellular Component: nucleus

Molecular Function:identical protein binding; protein binding; transcription factor activity

NCBI Summary:This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
UniProt Code:P57086
NCBI GenInfo Identifier:10720272
NCBI Gene ID:51282
NCBI Accession:P57086.1
UniProt Secondary Accession:P57086,Q6IAG7,
UniProt Related Accession:P57086
Molecular Weight:19,082 Da
NCBI Full Name:SCAN domain-containing protein 1
NCBI Synonym Full Names:SCAN domain containing 1
NCBI Official Symbol:SCAND1  
NCBI Official Synonym Symbols:RAZ1; SDP1  
NCBI Protein Information:SCAN domain-containing protein 1
UniProt Protein Name:SCAN domain-containing protein 1
Protein Family:SCAN domain-containing protein
UniProt Gene Name:SCAND1  
UniProt Entry Name:SCND1_HUMAN
Anti-SCAND1 Polyclonal Antibody (CAB8310)Western blot analysis of extracts of various cell lines, using SCAND1 antibody (CAB8310) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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