NCBI Summary: | This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010] |
UniProt Code: | Q9Y3Z3 |
NCBI GenInfo Identifier: | 38016914 |
NCBI Gene ID: | 25939 |
NCBI Accession: | NP_056289.2 |
UniProt Secondary Accession: | Q9Y3Z3,Q5JXG8, Q8N491, Q9H004, Q9H005, Q9H3U9, B4E2A5 E1P5V2, |
UniProt Related Accession: | Q9Y3Z3 |
Molecular Weight: | 68,122 Da |
NCBI Full Name: | deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
NCBI Synonym Full Names: | SAM domain and HD domain 1 |
NCBI Official Symbol: | SAMHD1 |
NCBI Official Synonym Symbols: | DCIP; CHBL2; HDDC1; MOP-5; SBBI88 |
NCBI Protein Information: | deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
UniProt Protein Name: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
UniProt Synonym Protein Names: | Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1 |
Protein Family: | Deoxynucleoside triphosphate triphosphohydrolase |
UniProt Gene Name: | SAMHD1 |
UniProt Entry Name: | SAMH1_HUMAN |