Cell Biology Antibodies 15

Anti-SACM1L Antibody (CAB8868)

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SKU:
CAB8868
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody

Description

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Antibody Name:Anti-SACM1L Antibody
Antibody SKU:CAB8868
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-520 of human SACM1L (NP_054735.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-520 of human SACM1L (NP_054735.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DRLS ILLD QVAE MQDE LSYF LVDS AGQV VANQ EGVF RSNC MDCL DRTN VIQS LLAR RSLQ AQLQ RLGV LHVG QKLE EQDE FEKI YKNA WADN ANAC AKQY AGTG ALKT DFTR TGKR THLG LIMD GWNS MIRY YKNN FSDG FRQD SIDL FLGN YSVD ELES HSPL SVPR DWK
Gene ID:22908
Uniprot:Q9NTJ5
Cellular Location:Endoplasmic reticulum membrane, Multi-pass membrane protein
Calculated MW:60kDa/66kDa
Observed MW:Refer to figures
Synonyms:SACM1L, SAC1
Background:This gene encodes an integral membrane protein that is localized to the endoplasmic reticulum and golgi, and functions as a phosphoinositide lipid phosphatase. Studies in mammals suggest that this gene is involved in the organization of golgi membranes and the mitotic spindles. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:SACM1L: Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2.
UniProt Protein Details:

Protein type:Phosphatase, lipid; Motility/polarity/chemotaxis; EC 3.1.3.-; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane

Molecular Function:phosphatidylinositol-3-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; phosphoric monoester hydrolase activity; protein binding

Biological Process: phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation

NCBI Summary:This gene encodes an integral membrane protein that is localized to the endoplasmic reticulum and golgi, and functions as a phosphoinositide lipid phosphatase. Studies in mammals suggest that this gene is involved in the organization of golgi membranes and the mitotic spindles. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]
UniProt Code:Q9NTJ5
NCBI GenInfo Identifier:167016563
NCBI Gene ID:22908
NCBI Accession:Q9NTJ5.2
UniProt Secondary Accession:Q9NTJ5,O94935, Q7LA14, Q7LA22, Q96AX7, Q9NQ46, Q9NQ57 A8K527, B4DK71,
UniProt Related Accession:Q9NTJ5
Molecular Weight:60,853 Da
NCBI Full Name:Phosphatidylinositide phosphatase SAC1
NCBI Synonym Full Names:SAC1 suppressor of actin mutations 1-like (yeast)
NCBI Official Symbol:SACM1L  
NCBI Official Synonym Symbols:SAC1  
NCBI Protein Information:phosphatidylinositide phosphatase SAC1
UniProt Protein Name:Phosphatidylinositide phosphatase SAC1
UniProt Synonym Protein Names:Suppressor of actin mutations 1-like protein
UniProt Gene Name:SACM1L  
UniProt Entry Name:SAC1_HUMAN
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